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MedKoo Cat#: 564610 | Name: DB1960

Description:

WARNING: This product is for research use only, not for human or veterinary use.

DB1960 is an antileishmanial agent against both intracellular Leishmania donovani and intracellular Leishmania amazonensis. DB1960 displays dose-dependent reduction of liver parasitemia.

Chemical Structure

DB1960
DB1960
CAS#NONE

Theoretical Analysis

MedKoo Cat#: 564610

Name: DB1960

CAS#: NONE

Chemical Formula: C36H42N6O9S2

Exact Mass: 766.2455

Molecular Weight: 766.89

Elemental Analysis: C, 56.38; H, 5.52; N, 10.96; O, 18.78; S, 8.36

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
DB-1960; DB 1960; DB1960
IUPAC/Chemical Name
2,5-bis[2-(2-isopropoxy)-4-(2-pyridylimino)aminophenyl]furan mesylate
InChi Key
JJKVIGFPSKCKJO-UHFFFAOYSA-N
InChi Code
InChI=1S/C34H34N6O3.2CH4O3S/c1-21(2)41-31-19-23(39-33(35)27-9-5-7-17-37-27)11-13-25(31)29-15-16-30(43-29)26-14-12-24(20-32(26)42-22(3)4)40-34(36)28-10-6-8-18-38-28;2*1-5(2,3)4/h5-22H,1-4H3,(H2,35,39)(H2,36,40);2*1H3,(H,2,3,4)
SMILES Code
N=C(C1=NC=CC=C1)NC(C=C2OC(C)C)=CC=C2C3=CC=C(C4=C(OC(C)C)C=C(NC(C5=CC=CC=N5)=N)C=C4)O3.OS(C)(=O)=O.OS(C)(=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 766.89 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Zhu X, Liu Q, Yang S, Parman T, Green CE, Mirsalis JC, de Nazaré Correia Soeiro M, Mello de Souza E, da Silva CF, da Gama Jaen Batista D, Stephens CE, Banerjee M, Farahat AA, Munde M, Wilson WD, Boykin DW, Wang MZ, Werbovetz KA. Evaluation of arylimidamides DB1955 and DB1960 as candidates against visceral leishmaniasis and Chagas' disease: in vivo efficacy, acute toxicity, pharmacokinetics, and toxicology studies. Antimicrob Agents Chemother. 2012 Jul;56(7):3690-9. doi: 10.1128/AAC.06404-11. Epub 2012 Apr 16. PubMed PMID: 22508306; PubMed Central PMCID: PMC3393454.