Clazamycin B | CAS# 71774-49-7 | Antibiotic

MedKoo Cat#: 573185 | Name: Clazamycin B

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Clazamycin B is an antibiotic.

Chemical Structure

Clazamycin B

CAS#71774-49-7

Theoretical Analysis

MedKoo Cat#: 573185

Name: Clazamycin B

CAS#: 71774-49-7

Chemical Formula: C7H9ClN2O

Exact Mass: 172.0403

Molecular Weight: 172.61

Elemental Analysis: C, 48.71; H, 5.26; Cl, 20.54; N, 16.23; O, 9.27

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Clazamycin B

IUPAC/Chemical Name

(2S-cis)-2-Chloro-5-imino-2,3-dihydro-1H-pyrrolizin-7a(5H)-ol

InChi Key

DVCHIDKMDZZKBR-CAHLUQPWSA-N

InChi Code

1S/C7H9ClN2O/c8-5-3-7(11)2-1-6(9)10(7)4-5/h1-2,5,9,11H,3-4H2/t5-,7+/m0/s1

SMILES Code

C1N2C(C=C[C@@]2(C[C@@H]1Cl)O)=N

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 172.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Buechter DD, Thurston DE. Studies on the pyrrolizidine antitumor agent, clazamycin: interconversion of clazamycins A and B. J Nat Prod. 1987 May-Jun;50(3):360-7. PubMed PMID: 3668555. 2: Hori M, Naito K, Sakata N, Uehara Y, Umezawa H. Inhibition of DNA replication and membrane transport of some nutrients by clazamycin in Escherichia coli. J Antibiot (Tokyo). 1984 Mar;37(3):260-6. PubMed PMID: 6373701. 3: Dolak LA, DeBoer C. Clazamycin B is antibiotic 354. J Antibiot (Tokyo). 1980 Jan;33(1):83-4. PubMed PMID: 7372554. 4: Horiuchi Y, Kondo S, Ikeda T, Ikeda D, Miura K, Hamada M, Takeuchi T, Umezawa H. New antibiotics clazamycins A and B. J Antibiot (Tokyo). 1979 Jul;32(7):762-4. PubMed PMID: 541271.