MedKoo Cat#: 573177 | Name: Pyrantel pamoate
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pyrantel pamoate is a broad spectrum antinematodal anthelmintic.

Chemical Structure

Pyrantel pamoate
Pyrantel pamoate
CAS#22204-24-6

Theoretical Analysis

MedKoo Cat#: 573177

Name: Pyrantel pamoate

CAS#: 22204-24-6

Chemical Formula: C34H30N2O6S

Exact Mass: 594.1825

Molecular Weight: 594.68

Elemental Analysis: C, 68.67; H, 5.09; N, 4.71; O, 16.14; S, 5.39

Price and Availability

Size Price Availability Quantity
5g USD 210.00
10g USD 345.00
50g USD 625.00
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Related CAS #
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Synonym
Pyrantel pamoate
IUPAC/Chemical Name
(E)-1,4,5,6-Tetrahydro-1-methyl-2-(2-(2-thienyl)vinyl)pyrimidine 4,4'-methylenebis(3-hydroxy-2-naphthoate) (1:1)
InChi Key
AQXXZDYPVDOQEE-MXDQRGINSA-N
InChi Code
1S/C23H16O6.C11H14N2S/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;1-13-8-3-7-12-11(13)6-5-10-4-2-9-14-10/h1-10,24-25H,11H2,(H,26,27)(H,28,29);2,4-6,9H,3,7-8H2,1H3/b;6-5+
SMILES Code
CN1CCCN=C1/C=C/c2cccs2.c1ccc2c(c1)cc(c(c2Cc3c4ccccc4cc(c3O)C(=O)O)O)C(=O)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 594.68 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Moser W, Sayasone S, Xayavong S, Bounheuang B, Puchkov M, Huwyler J, Hattendorf J, Keiser J. Efficacy and tolerability of triple drug therapy with albendazole, pyrantel pamoate, and oxantel pamoate compared with albendazole plus oxantel pamoate, pyrantel pamoate plus oxantel pamoate, and mebendazole plus pyrantel pamoate and oxantel pamoate against hookworm infections in school-aged children in Laos: a randomised, single-blind trial. Lancet Infect Dis. 2018 Jul;18(7):729-737. doi: 10.1016/S1473-3099(18)30220-2. Epub 2018 Apr 16. PubMed PMID: 29673735. 2: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from http://www.ncbi.nlm.nih.gov/books/NBK501733/ PubMed PMID: 30000792. 3: Hu Y, Miller M, Zhang B, Nguyen TT, Nielsen MK, Aroian RV. In vivo and in vitro studies of Cry5B and nicotinic acetylcholine receptor agonist anthelmintics reveal a powerful and unique combination therapy against intestinal nematode parasites. PLoS Negl Trop Dis. 2018 May 18;12(5):e0006506. doi: 10.1371/journal.pntd.0006506. eCollection 2018 May. PubMed PMID: 29775454; PubMed Central PMCID: PMC5979042. 4: Arion A, Fernández-Varón E, Cárceles CM, Gagyi L, Ognean L. Pharmacokinetics of praziquantel and pyrantel pamoate combination following oral administration in cats. J Feline Med Surg. 2018 Oct;20(10):900-904. doi: 10.1177/1098612X17734065. Epub 2017 Oct 11. PubMed PMID: 29017390. 5: Whitehouse-Tedd KM, Smith L, Budd JA, Lloyd CG. Suspected adverse reactions to oral administration of a praziquantel-pyrantel combination in captive cheetahs (Acinonyx jubatus). J Am Vet Med Assoc. 2017 Nov 15;251(10):1188-1195. doi: 10.2460/javma.251.10.1188. PubMed PMID: 29099259.