MedKoo Cat#: 572537 | Name: DUN 00598
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

DUN 00598, also known as N-(Hydroxy-PEG3)-N-Boc-PEG4-t-butyl ester is a branched PEG derivative with a terminal hydroxy group, t-butyl ester, and a Boc protected amino group. The hydroxy group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under mild acidic conditions. The protected amine can be deprotected by acidic conditions. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Chemical Structure

DUN 00598
DUN 00598
CAS#NONE

Theoretical Analysis

MedKoo Cat#: 572537

Name: DUN 00598

CAS#: NONE

Chemical Formula: C28H55NO12

Exact Mass: 597.3724

Molecular Weight: 597.74

Elemental Analysis: C, 56.26; H, 9.27; N, 2.34; O, 32.12

Price and Availability

Size Price Availability Quantity
100mg USD 600.00 2 Weeks
250mg USD 1,050.00 2 Weeks
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Related CAS #
No Data
Synonym
N-(Hydroxy-PEG3)-N-Boc-PEG4-t-butyl ester; N-(Hydroxy-PEG3)-N-Boc-PEG4-Boc; DUN 00598; DUN-00598; DUN00598
IUPAC/Chemical Name
tert-butyl 12-(tert-butoxycarbonyl)-1-hydroxy-3,6,9,15,18,21,24-heptaoxa-12-azaheptacosan-27-oate
InChi Key
DSCNYBQOSCPDBB-UHFFFAOYSA-N
InChi Code
InChI=1S/C28H55NO12/c1-27(2,3)40-25(31)7-11-33-15-19-37-23-24-39-21-17-35-13-9-29(26(32)41-28(4,5)6)8-12-34-16-20-38-22-18-36-14-10-30/h30H,7-24H2,1-6H3
SMILES Code
OCCOCCOCCOCCN(C(OC(C)(C)C)=O)CCOCCOCCOCCOCCC(OC(C)(C)C)=O
Appearance
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 597.74 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Brown A, Patel S, Ward C, Lorenz A, Ortiz M, DuRoss A, Wieghardt F, Esch A, Otten EG, Heiser LM, Korolchuk VI, Sun C, Sarkar S, Sahay G. PEG-lipid micelles enable cholesterol efflux in Niemann-Pick Type C1 disease-based lysosomal storage disorder. Sci Rep. 2016 Aug 30;6:31750. doi: 10.1038/srep31750. PubMed PMID: 27572704; PubMed Central PMCID: PMC5004151. 2: Saifer MG, Williams LD, Sobczyk MA, Michaels SJ, Sherman MR. Selectivity of binding of PEGs and PEG-like oligomers to anti-PEG antibodies induced by methoxyPEG-proteins. Mol Immunol. 2014 Feb;57(2):236-46. doi: 10.1016/j.molimm.2013.07.014. Epub 2013 Nov 5. PubMed PMID: 24200843. 3: Garay RP, El-Gewely R, Armstrong JK, Garratty G, Richette P. Antibodies against polyethylene glycol in healthy subjects and in patients treated with PEG-conjugated agents. Expert Opin Drug Deliv. 2012 Nov;9(11):1319-23. doi: 10.1517/17425247.2012.720969. Epub 2012 Aug 30. PubMed PMID: 22931049.