MedKoo Cat#: 555375 | Name: CUDC-908
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

CUDC-908, also known as MDK9521, BEBT 908, PI3Kα inhibitor 1 and PI3Kα-IN-243 , is a potent PI3Kα inhibitor. MDK9521 was reported in patent US/20120088764A1. MDK9521 has CAS#1235449-52-1.

Chemical Structure

CUDC-908
CUDC-908
CAS#1235449-52-1

Theoretical Analysis

MedKoo Cat#: 555375

Name: CUDC-908

CAS#: 1235449-52-1

Chemical Formula: C23H25N9O3S

Exact Mass: 507.1801

Molecular Weight: 507.57

Elemental Analysis: C, 54.43; H, 4.96; N, 24.84; O, 9.46; S, 6.32

Price and Availability

Size Price Availability Quantity
100mg USD 750.00 2 Weeks
200mg USD 1,350.00 2 Weeks
500mg USD 2,250.00 2 Weeks
1g USD 2,950.00 2 Weeks
2g USD 4,950.00 2 Weeks
5g USD 7,950.00 2 Weeks
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Related CAS #
Synonym
PI3Kα inhibitor 1; MDK9521; MDK-9521; MDK 9521; PI3Kα-IN-243; BEBT-908; BEBT908; BEBT 908; CUDC-908; CUDC 908; CUDC908; Ifupinostat;
IUPAC/Chemical Name
N-hydroxy-2-(methyl((2-(6-(methylamino)pyridin-3-yl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)amino)pyrimidine-5-carboxamide
InChi Key
TWJZFXHSPBBPNI-UHFFFAOYSA-N
InChi Code
InChI=1S/C23H25N9O3S/c1-24-18-4-3-14(10-25-18)20-28-17-9-16(36-19(17)21(29-20)32-5-7-35-8-6-32)13-31(2)23-26-11-15(12-27-23)22(33)30-34/h3-4,9-12,34H,5-8,13H2,1-2H3,(H,24,25)(H,30,33)
SMILES Code
O=C(C1=CN=C(N(C)CC2=CC3=NC(C4=CC=C(NC)N=C4)=NC(N5CCOCC5)=C3S2)N=C1)NO
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 507.57 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
[1]. Cai Xiong, et al. Deazapurines, thienopyrimidines and furopyrimidines as phosphoinositide 3-kinase inhibitors with a zinc binding moiety and their preparation and use in the treatment of diseases. From U.S. Pat. Appl. Publ. (2012), US 20120088764 A1 20120 https://patents.google.com/patent/US20120088764A1