MedKoo Cat#: 564534 | Name: Medioresinol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Medioresinol is a natural lesishmanicidal agent which reduces cardiovascular disease risk, and induces intracellular ROS accumulation and mitochondria-mediated apoptotic cell death in Candida albicans.

Chemical Structure

Medioresinol
Medioresinol
CAS#40957-99-1

Theoretical Analysis

MedKoo Cat#: 564534

Name: Medioresinol

CAS#: 40957-99-1

Chemical Formula: C21H24O7

Exact Mass: 388.1522

Molecular Weight: 388.42

Elemental Analysis: C, 64.94; H, 6.23; O, 28.83

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Medioresil, Medioresinol
IUPAC/Chemical Name
4-[(3S,3aR,6S,6aR)-3-(4-Hydroxy-3-methoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-yl]-2,6-dimethoxyphenol
InChi Key
VJOBNGRIBLNUKN-BMHXQBNDSA-N
InChi Code
InChI=1S/C21H24O7/c1-24-16-6-11(4-5-15(16)22)20-13-9-28-21(14(13)10-27-20)12-7-17(25-2)19(23)18(8-12)26-3/h4-8,13-14,20-23H,9-10H2,1-3H3/t13-,14-,20+,21+/m0/s1
SMILES Code
OC1=C(OC)C=C([C@H]2OC[C@@]3([H])[C@]2([H])CO[C@@H]3C4=CC=C(O)C(OC)=C4)C=C1OC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 388.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Hwang JH, Choi H, Hwang IS, Kim AR, Woo ER, Lee DG. Synergistic antibacterial and antibiofilm effect between (+)-medioresinol and antibiotics in vitro. Appl Biochem Biotechnol. 2013 Aug;170(8):1934-41. PubMed PMID: 23797511. 2: Hwang JH, Hwang IS, Liu QH, Woo ER, Lee DG. (+)-Medioresinol leads to intracellular ROS accumulation and mitochondria-mediated apoptotic cell death in Candida albicans. Biochimie. 2012 Aug;94(8):1784-93. doi: 10.1016/j.biochi.2012.04.010. Epub 2012 Apr 16. PubMed PMID: 22534194.