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MedKoo Cat#: 564522 | Name: Hippeastrine Hydrobromide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Hippeastrine hydrobromide is a natural alkaloid which demonstrates significant cytotoxicity against a panel of human and murine tumor cell lines.

Chemical Structure

Hippeastrine Hydrobromide
Hippeastrine Hydrobromide
CAS#22352-41-6 (HBr)

Theoretical Analysis

MedKoo Cat#: 564522

Name: Hippeastrine Hydrobromide

CAS#: 22352-41-6 (HBr)

Chemical Formula: C17H18BrNO5

Exact Mass: 395.0368

Molecular Weight: 396.24

Elemental Analysis: C, 51.53; H, 4.58; Br, 20.17; N, 3.54; O, 20.19

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
477-17-8 (free base) 22352-41-6 (HBr)
Synonym
(+)-Hippeastrine HBr; Hippeastrine HBr; Hippeastrine hydrobromide
IUPAC/Chemical Name
(5S,5aS,12bS)-5-hydroxy-1-methyl-2,3,5,5a,12b,12c-hexahydro-[1,3]dioxolo[4',5':6,7]isochromeno[3,4-g]indol-7(1H)-one hydrobromide
InChi Key
JXIXDPWKBCBXEY-XCIKPZSDSA-N
InChi Code
InChI=1S/C17H17NO5.BrH/c1-18-3-2-8-4-11(19)16-14(15(8)18)9-5-12-13(22-7-21-12)6-10(9)17(20)23-16;/h4-6,11,14-16,19H,2-3,7H2,1H3;1H/t11-,14-,15?,16+;/m0./s1
SMILES Code
O=C(O1)C2=CC(OCO3)=C3C=C2[C@]4([H])[C@@]1([H])[C@@H](O)C=C5CCN(C)C45.[H]Br
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 396.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Zhou T, Tan L, Cederquist GY, Fan Y, Hartley BJ, Mukherjee S, Tomishima M, Brennand KJ, Zhang Q, Schwartz RE, Evans T, Studer L, Chen S. High-Content Screening in hPSC-Neural Progenitors Identifies Drug Candidates that Inhibit Zika Virus Infection in Fetal-like Organoids and Adult Brain. Cell Stem Cell. 2017 Aug 3;21(2):274-283.e5. doi: 10.1016/j.stem.2017.06.017. Epub 2017 Jul 20. PubMed PMID: 28736217; PubMed Central PMCID: PMC5553280.