Glyclopyramide | 631-27-6 | treatment of diabetes

MedKoo Cat#: 581613 | Name: Glyclopyramide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Glyclopyramide is a sulfonylurea drug used in the treatment of diabetes.

Chemical Structure

Glyclopyramide

CAS#631-27-6

Theoretical Analysis

MedKoo Cat#: 581613

Name: Glyclopyramide

CAS#: 631-27-6

Chemical Formula: C11H14ClN3O3S

Exact Mass: 303.0444

Molecular Weight: 303.76

Elemental Analysis: C, 43.50; H, 4.65; Cl, 11.67; N, 13.83; O, 15.80; S, 10.55

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Glyclopyramide; Gliclopiramida; Glyclopyramidum.

IUPAC/Chemical Name

1-((p-Chlorophenyl)sulfonyl)-3-(1-pyrrolidinyl)urea

InChi Key

HNSCCNJWTJUGNQ-UHFFFAOYSA-N

InChi Code

InChI=1S/C11H14ClN3O3S/c12-9-3-5-10(6-4-9)19(17,18)14-11(16)13-15-7-1-2-8-15/h3-6H,1-2,7-8H2,(H2,13,14,16)

SMILES Code

O=C(NN1CCCC1)NS(=O)(C2=CC=C(Cl)C=C2)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 303.76 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Dumpati R, Ramatenki V, Vadija R, Vellanki S, Vuruputuri U. Structural insights into suppressor of cytokine signaling 1 protein- identification of new leads for type 2 diabetes mellitus. J Mol Recognit. 2018 Jul;31(7):e2706. doi: 10.1002/jmr.2706. Epub 2018 Apr 6. PubMed PMID: 29630758. 2: Ozawa H, Murai Y, Ozawa T. [A 50-year history of new drugs in Japan-the development and progress of anti-diabetic drugs and the epidemiological aspects of diabetes mellitus]. Yakushigaku Zasshi. 2003;38(1):11-27. Japanese. PubMed PMID: 14570054. 3: Yamagata S, Goto Y, Oneda A, Kikuchi J, Toyota T. Clinical evaluation of the effect of glyclopyramide in diabetes mellitus. Tohoku J Exp Med. 1969 Jun;98(2):155-69. PubMed PMID: 5811101.