DMB213 | Zika RdRp Inhibitor

MedKoo Cat#: 564473 | Name: DMB213

Description:

WARNING: This product is for research use only, not for human or veterinary use.

DMB213 is a non-nucleoside inhibitor of Zika viral RNA-dependent RNA polymerase (RdRp) enzymes.

Chemical Structure

DMB213

CAS#NONE

Theoretical Analysis

MedKoo Cat#: 564473

Name: DMB213

CAS#: NONE

Chemical Formula: C8H9N5O4

Exact Mass: 239.0655

Molecular Weight: 239.19

Elemental Analysis: C, 40.17; H, 3.79; N, 29.28; O, 26.76

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

DMB-213; DMB 213; DMB213

IUPAC/Chemical Name

5-Azidomethyl-3-hydroxy-4-hydroxymethyl-pyridine-2-carboxylic acid hydroxyamide

InChi Key

SCKJVXBSEBHVLQ-UHFFFAOYSA-N

InChi Code

InChI=1S/C8H9N5O4/c9-13-11-2-4-1-10-6(8(16)12-17)7(15)5(4)3-14/h1,14-15,17H,2-3H2,(H,12,16)

SMILES Code

O=C(C1=NC=C(CN=[N+]=[N-])C(CO)=C1O)NO

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 239.19 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Xu HT, Hassounah SA, Colby-Germinario SP, Oliveira M, Fogarty C, Quan Y, Han Y, Golubkov O, Ibanescu I, Brenner B, Stranix BR, Wainberg MA. Purification of Zika virus RNA-dependent RNA polymerase and its use to identify small-molecule Zika inhibitors. J Antimicrob Chemother. 2017 Mar 1;72(3):727-734. doi: 10.1093/jac/dkw514. PubMed PMID: 28069884; PubMed Central PMCID: PMC5890664.