SC 32855 | CAS#76053-14-0 | benzodiazepine

MedKoo Cat#: 461868 | Name: SC 32855

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SC 32855 is a 1,4-benzodiazepine that has been shown to arrest of spermatogenesis and degeneration of the germinal epithelium.

Chemical Structure

SC 32855

CAS#76053-14-0

Theoretical Analysis

MedKoo Cat#: 461868

Name: SC 32855

CAS#: 76053-14-0

Chemical Formula: C18H15Cl2N3O

Exact Mass: 359.0592

Molecular Weight: 360.23

Elemental Analysis: C, 60.02; H, 4.20; Cl, 19.68; N, 11.66; O, 4.44

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

SC 32855; SC-32855; SC32855;

IUPAC/Chemical Name

2-(7-chloro-5-(2-chlorophenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-1-yl)-4,5-dihydrooxazole

InChi Key

JNOGAOFNWOYRTM-UHFFFAOYSA-N

InChi Code

InChI=1S/C18H15Cl2N3O/c19-12-5-6-16-14(11-12)17(13-3-1-2-4-15(13)20)21-7-9-23(16)18-22-8-10-24-18/h1-6,11H,7-10H2

SMILES Code

ClC1=CC=CC=C1C2=NCCN(C3=NCCO3)C4=CC=C(Cl)C=C24

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 360.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Chengelis CP, Dodd DC, Kotsonis FN. Testicular toxicity of a novel 1,4-benzodiazepine (SC-32855) in rats and dogs. Res Commun Chem Pathol Pharmacol. 1986 Jan;51(1):23-36. PubMed PMID: 3952369. 2: Means JR, Chengelis CP, Jasty V. Testicular toxicity induced by oral administration of SC-32855, A 1,4-benzodiazepine, in the dog. Res Commun Chem Pathol Pharmacol. 1982 Aug;37(2):317-20. PubMed PMID: 6127762. 3: Piotrowska A, Kwiatkowski K, Rojewska E, Slusarczyk J, Makuch W, Basta-Kaim A, Przewlocka B, Mika J. Direct and indirect pharmacological modulation of CCL2/CCR2 pathway results in attenuation of neuropathic pain - In vivo and in vitro evidence. J Neuroimmunol. 2016 Aug 15;297:9-19. doi: 10.1016/j.jneuroim.2016.04.017. Epub 2016 May 3. PubMed PMID: 27397071.