O-Demethyldeacetyldiltiazem | 84903-82-2

MedKoo Cat#: 581588 | Name: O-Demethyldeacetyldiltiazem

Description:

WARNING: This product is for research use only, not for human or veterinary use.

O-Demethyldeacetyldiltiazem is one of the diltiazem metabolites in human plasma.

Chemical Structure

O-Demethyldeacetyldiltiazem

CAS#84903-82-2

Theoretical Analysis

MedKoo Cat#: 581588

Name: O-Demethyldeacetyldiltiazem

CAS#: 84903-82-2

Chemical Formula: C19H22N2O3S

Exact Mass: 358.1351

Molecular Weight: 358.46

Elemental Analysis: C, 63.66; H, 6.19; N, 7.82; O, 13.39; S, 8.94

Price and Availability

This product was removed for the commercial reasons.

Related CAS #

No Data

Synonym

O-Demethyldeacetyldiltiazem; Deacetyl-O-demethyl-D-diltiazem; Deacetyl-O-demethyldiltiazem; Deacetyl o-desmethyl diltiazem.

IUPAC/Chemical Name

1,5-Benzothiazepin-4(5H)-one, 5-(2-(dimethylamino)ethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-, (2S,3S)-

InChi Key

QYKYTLTVPBXRNC-MSOLQXFVSA-N

InChi Code

InChI=1S/C19H22N2O3S/c1-20(2)11-12-21-15-5-3-4-6-16(15)25-18(17(23)19(21)24)13-7-9-14(22)10-8-13/h3-10,17-18,22-23H,11-12H2,1-2H3/t17-,18+/m1/s1

SMILES Code

O=C1[C@H](O)[C@H](C2=CC=C(O)C=C2)SC3=CC=CC=C3N1CCN(C)C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 358.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Hussain MD, Tam YK, Finegan BA, Coutts RT. Simple and sensitive high-performance liquid chromatographic method for the determination of diltiazem and six of its metabolites in human plasma. J Chromatogr. 1992 Nov 6;582(1-2):203-9. PubMed PMID: 1491042.