MedKoo Cat#: 581583 | Name: Deacetylcefotaxime lactone
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Deacetylcefotaxime lactone also known as 3-Desacetyl Cefotaxime Lactone, is a degradation product for other cephalosporin antibiotics. 3-Desacetyl Cefotaxime Lactone is an impurity of Cefotaxime sodium (C242950).

Chemical Structure

Deacetylcefotaxime lactone
Deacetylcefotaxime lactone
CAS#66340-33-8

Theoretical Analysis

MedKoo Cat#: 581583

Name: Deacetylcefotaxime lactone

CAS#: 66340-33-8

Chemical Formula: C14H13N5O5S2

Exact Mass: 395.0358

Molecular Weight: 395.41

Elemental Analysis: C, 42.53; H, 3.31; N, 17.71; O, 20.23; S, 16.22

Price and Availability

Size Price Availability Quantity
10mg USD 450.00 2 Weeks
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Related CAS #
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Synonym
Deacetylcefotaxime lactone; 3-Desacetyl Cefotaxime Lactone; Ceftriaxone impurity B
IUPAC/Chemical Name
(5aR,6R)-6-(((2Z)-2-(2-Aminothiazol-4-yl)-2-(methoxyimino)acetyl)amino)-5a,6-dihydro-3H,7H-azeto(2,1-b)furo(3,4-d)(1,3)thiazine-1,7(4H)-dione
InChi Key
MCSWUKXFFGUOQE-GHXIOONMSA-N
InChi Code
InChI=1S/C14H13N5O5S2/c1-23-18-7(6-4-26-14(15)16-6)10(20)17-8-11(21)19-9-5(2-24-13(9)22)3-25-12(8)19/h4,8,12H,2-3H2,1H3,(H2,15,16)(H,17,20)/b18-7-/t8-,12-/m1/s1
SMILES Code
O=C1OCC2=C1N3[C@]([C@H](NC(/C(C4=CSC(N)=N4)=N\OC)=O)C3=O)([H])SC2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 395.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Coombes JD. Metabolism of cefotaxime in animals and humans. Rev Infect Dis. 1982 Sep-Oct;4 Suppl:S325-32. PubMed PMID: 6294781.