DODMA | MBN 305A | CAS#104162-47-2

MedKoo Cat#: 555353 | Name: DODMA

Description:

WARNING: This product is for research use only, not for human or veterinary use.

DODMA, also known as MBN 305A is a cationic lipid containing the unsaturated long-chain (18:1) oleic acid inserted at both the sn-1 and sn-2 positions. It has been used in the composition of lipospomes formulated as stable nucleic acid lipid particles that can encapsulate siRNA or other small molecules to be used for drug delivery.

Chemical Structure

DODMA

CAS#104162-47-2

Theoretical Analysis

MedKoo Cat#: 555353

Name: DODMA

CAS#: 104162-47-2

Chemical Formula: C41H81NO2

Exact Mass: 619.6267

Molecular Weight: 620.10

Elemental Analysis: C, 79.41; H, 13.17; N, 2.26; O, 5.16

Price and Availability

Size	Price	Availability
25mg	USD 90.00	Ready to ship
50mg	USD 150.00	Ready to ship
100mg	USD 225.00	Ready to ship
200mg	USD 350.00	Ready to ship
500mg	USD 550.00	Ready to ship
1g	USD 850.00	Ready to ship
2g	USD 1,350.00	Ready to ship
5g	USD 2,950.00	Ready to ship

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Related CAS #

No Data

Synonym

MBN 305A; MBN305A; MBN-305A; DODMA;

IUPAC/Chemical Name

1,2-Dioleyloxy-3-dimethylamino-propane

InChi Key

GLGLUQVVDHRLQK-WRBBJXAJSA-N

InChi Code

InChI=1S/C41H81NO2/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-43-40-41(39-42(3)4)44-38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h19-22,41H,5-18,23-40H2,1-4H3/b21-19-,22-20-

SMILES Code

CN(CC(OCCCCCCCC/C=C\CCCCCCCC)COCCCCCCCC/C=C\CCCCCCCC)C

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Product Data

Product Data

Certificate of Analysis

View CoA: current batch, Lot#A23T09K11

QC Data

View QC data: current batch, Lot#A23T09K11

Safety Data Sheet (SDS)

View Safety Data Sheet (SDS)

Instruction

View handling instruction

Biological target:

DODMA, a cationic lipid, is used for the preparation of liposomes.

In vitro activity:

TBD

In vivo activity:

TBD

	Solvent	mg/mL	mM
Solubility
	DMF	12.0	19.35
	DMSO	100.0	161.26
	Ethanol	10.0	0.16

Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 620.10 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:

TBD

In vitro protocol:

TBD

In vivo protocol:

TBD

1: Mok KW, Lam AM, Cullis PR. Stabilized plasmid-lipid particles: factors influencing plasmid entrapment and transfection properties. Biochim Biophys Acta. 1999 Jul 15;1419(2):137-50. PubMed PMID: 10407066.