MedKoo Cat#: 564340 | Name: USL311
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

USL311 is a selective inhibitor of fatty acid synthase (FASN), a key enzyme involved in lipid biosynthesis, with potential applications in oncology and neurodegenerative diseases. It has demonstrated the ability to cross the blood-brain barrier, making it a promising candidate for treating glioblastoma and other central nervous system disorders. USL311 is currently being investigated in clinical trials for its efficacy in targeting cancer metabolism and improving patient outcomes.

Chemical Structure

USL311
USL311
CAS#1373268-67-7

Theoretical Analysis

MedKoo Cat#: 564340

Name: USL311

CAS#: 1373268-67-7

Chemical Formula: C24H34N6O

Exact Mass: 422.2794

Molecular Weight: 422.58

Elemental Analysis: C, 68.22; H, 8.11; N, 19.89; O, 3.79

Price and Availability

Size Price Availability Quantity
50mg USD 450.00 2 Weeks
100mg USD 750.00 2 Weeks
200mg USD 1,350.00 2 Weeks
500mg USD 2,850.00 2 Weeks
1g USD 4,250.00 2 Weeks
2g USD 6,850.00 2 Weeks
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Related CAS #
No Data
Synonym
USL-311; USL 311; USL311
IUPAC/Chemical Name
6-[4-(1-Propan-2-ylpiperidin-4-yl)-1,4-diazepan-1-yl]-N-pyridin-4-ylpyridine-2-carboxamide
InChi Key
XNUNVQKARNSSEO-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H34N6O/c1-19(2)28-15-9-21(10-16-28)29-13-4-14-30(18-17-29)23-6-3-5-22(27-23)24(31)26-20-7-11-25-12-8-20/h3,5-8,11-12,19,21H,4,9-10,13-18H2,1-2H3,(H,25,26,31)
SMILES Code
O=C(C1=NC(N2CCN(C3CCN(C(C)C)CC3)CCC2)=CC=C1)NC4=CC=NC=C4
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 422.58 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Takacs GP, Flores-Toro JA, Harrison JK. Modulation of the chemokine/chemokine receptor axis as a novel approach for glioma therapy. Pharmacol Ther. 2021 Jun;222:107790. doi: 10.1016/j.pharmthera.2020.107790. Epub 2020 Dec 11. PMID: 33316289; PMCID: PMC8122077.