E738 is an inhibitor of both TGFβ and BMP pathways through ubiquitin-proteasome-mediated depletion of total R-Smad pools. E738 is an enhancer of p38 and JNK phosphorylation involved in Smad-independent TGFβ/BMP signaling.
MedKoo Cat#: 564224
Name: E738
CAS#: NONE
Chemical Formula: C20H19N3O5
Exact Mass: 381.1325
Molecular Weight: 381.39
Elemental Analysis: C, 62.99; H, 5.02; N, 11.02; O, 20.97
The following data is based on the product molecular weight 381.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
