MedKoo Cat#: 527944 | Name: Lucidenic acid G

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lucidenic acid G is a bio active chemical.

Chemical Structure

Lucidenic acid G
Lucidenic acid G
CAS#102607-21-6

Theoretical Analysis

MedKoo Cat#: 527944

Name: Lucidenic acid G

CAS#: 102607-21-6

Chemical Formula: C27H40O7

Exact Mass: 476.2774

Molecular Weight: 476.61

Elemental Analysis: C, 68.04; H, 8.46; O, 23.50

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Lucidenic acid G
IUPAC/Chemical Name
CHOL-8-EN-24-oic acid, 7,15-dihydroxy-4-(hydroxymethyl)-4,14-dimethyl-3,11-dioxo-, (4beta,5alpha,7beta,15alpha)-
InChi Key
PWSMDKBWXADYJS-HPMFNFBQSA-N
InChi Code
InChI=1S/C27H40O7/c1-14(6-7-21(33)34)15-10-20(32)27(5)23-16(29)11-18-24(2,9-8-19(31)25(18,3)13-28)22(23)17(30)12-26(15,27)4/h14-16,18,20,28-29,32H,6-13H2,1-5H3,(H,33,34)/t14-,15-,16+,18-,20+,24+,25-,26-,27+/m1/s1
SMILES Code
C[C@H](CCC(O)=O)[C@H]([C@]1(C2)C)C[C@H](O)[C@@]1(C)C([C@@H](O)C[C@@]3([H])[C@@](C)(CO)C(CC[C@]43C)=O)=C4C2=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 476.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Che XQ, Li SP, Zhao J. [Ganoderma triterpenoids from aqueous extract of Ganoderma lucidum]. Zhongguo Zhong Yao Za Zhi. 2017 May;42(10):1908-1915. doi: 10.19540/j.cnki.cjcmm.20170412.001. Chinese. PubMed PMID: 29090550. 2: Sahoo AK, Dash UC, Kanhar S, Mahapatra AK. In vitro biological assessment of Homalium zeylanicum and isolation of lucidenic acid A triterpenoid. Toxicol Rep. 2017 Jun 4;4:274-281. doi: 10.1016/j.toxrep.2017.04.004. eCollection 2017. PubMed PMID: 28959649; PubMed Central PMCID: PMC5615128. 3: Wu L, Liang W, Chen W, Li S, Cui Y, Qi Q, Zhang L. Screening and Analysis of the Marker Components in Ganoderma lucidum by HPLC and HPLC-MS(n) with the Aid of Chemometrics. Molecules. 2017 Apr 6;22(4). pii: E584. doi: 10.3390/molecules22040584. PubMed PMID: 28383512. 4: Watanabe K, Shuto T, Sato M, Onuki K, Mizunoe S, Suzuki S, Sato T, Koga T, Suico MA, Kai H, Ikeda T. Lucidenic acids-rich extract from antlered form of Ganoderma lucidum enhances TNFα induction in THP-1 monocytic cells possibly via its modulation of MAP kinases p38 and JNK. Biochem Biophys Res Commun. 2011 Apr 29;408(1):18-24. doi: 10.1016/j.bbrc.2011.03.108. Epub 2011 Mar 29. PubMed PMID: 21453678. 5: Seo HW, Hung TM, Na M, Jung HJ, Kim JC, Choi JS, Kim JH, Lee HK, Lee I, Bae K, Hattori M, Min BS. Steroids and triterpenes from the fruit bodies of Ganoderma lucidum and their anti-complement activity. Arch Pharm Res. 2009 Nov;32(11):1573-9. doi: 10.1007/s12272-009-2109-x. PubMed PMID: 20091270. 6: Hsu CL, Yu YS, Yen GC. Lucidenic acid B induces apoptosis in human leukemia cells via a mitochondria-mediated pathway. J Agric Food Chem. 2008 Jun 11;56(11):3973-80. doi: 10.1021/jf800006u. Epub 2008 May 16. PubMed PMID: 18481862. 7: Weng CJ, Chau CF, Chen KD, Chen DH, Yen GC. The anti-invasive effect of lucidenic acids isolated from a new Ganoderma lucidum strain. Mol Nutr Food Res. 2007 Dec;51(12):1472-7. PubMed PMID: 17979098. 8: Luo J, Lin ZB. [A new triterpene from the fruiting bodies of Ganoderma lucidum]. Yao Xue Xue Bao. 2001 Aug;36(8):595-8. Chinese. PubMed PMID: 12579936. 9: Wu TS, Shi LS, Kuo SC. Cytotoxicity of Ganoderma lucidum triterpenes. J Nat Prod. 2001 Aug;64(8):1121-2. PubMed PMID: 11520245.