SGC-AAK1-1N | CAS#2247894-32-0 | SGC-AAK1-1 negative control

MedKoo Cat#: 564188 | Name: SGC-AAK1-1N

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

SGC-AAK1-1N is a negative control for SGC-AAK1-1.

Chemical Structure

SGC-AAK1-1N

CAS#2247894-32-0

Theoretical Analysis

MedKoo Cat#: 564188

Name: SGC-AAK1-1N

CAS#: 2247894-32-0

Chemical Formula: C20H22N4O3S

Exact Mass: 398.1413

Molecular Weight: 398.48

Elemental Analysis: C, 60.28; H, 5.57; N, 14.06; O, 12.04; S, 8.05

Price and Availability

Size	Price	Availability	Quantity
5mg	USD 350.00	2 Weeks

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Related CAS #

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Synonym

SGC-AAK1-1N; SGCAAK1-1N; SGC AAK1-1N; SGC-AAK11N; SGC-AAK1 1N; SGCAAK11N; SGC AAK1 1N;

IUPAC/Chemical Name

N-(6-(3-(Cyclopropanesulfonamido)phenyl)-1H-indazol-3-yl)isobutyramide

InChi Key

RAIAORGFMNXPOV-UHFFFAOYSA-N

InChi Code

InChI=1S/C20H22N4O3S/c1-12(2)20(25)21-19-17-9-6-14(11-18(17)22-23-19)13-4-3-5-15(10-13)24-28(26,27)16-7-8-16/h3-6,9-12,16,24H,7-8H2,1-2H3,(H2,21,22,23,25)

SMILES Code

CC(C)C(NC1=NNC2=C1C=CC(C3=CC=CC(NS(=O)(C4CC4)=O)=C3)=C2)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

	Solvent	mg/mL	mM
Solubility
	DMSO	39.9	100.00
	Ethanol	4.0	10.00

Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 398.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Agajanian MJ, Walker MP, Axtman AD, et al. WNT Activates the AAK1 Kinase to Promote Clathrin-Mediated Endocytosis of LRP6 and Establish a Negative Feedback Loop. Cell Rep. 2019;26(1):79-93.e8. doi:10.1016/j.celrep.2018.12.023

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