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MedKoo Cat#: 577261 | Name: Methenamine borate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Methenamine borate is an anti-infective agent most commonly used in the treatment of urinary tract infections. Its anti-infective action derives from the slow release of formaldehyde by hydrolysis at acidic pH.

Chemical Structure

Methenamine borate
Methenamine borate
CAS#27401-86-1

Theoretical Analysis

MedKoo Cat#: 577261

Name: Methenamine borate

CAS#: 27401-86-1

Chemical Formula: C6H15BN4O3

Exact Mass: 202.1237

Molecular Weight: 202.02

Elemental Analysis: C, 35.67; H, 7.48; B, 5.35; N, 27.73; O, 23.76

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Borohexamine; Methenamine borate; Urotropin borate
IUPAC/Chemical Name
1,3,5,7-tetraazaadamantane borate
InChi Key
MWWHVOZLSBBRDS-UHFFFAOYSA-N
InChi Code
InChI=1S/C6H12N4.BH3O3/c1-7-2-9-4-8(1)5-10(3-7)6-9;2-1(3)4/h1-6H2;2-4H
SMILES Code
OB(O)O.C1N2CN3CN(CN1C3)C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 202.02 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Barclay J, Veeratterapillay R, Harding C. Non-antibiotic options for recurrent urinary tract infections in women. BMJ. 2017 Nov 23;359:j5193. doi: 10.1136/bmj.j5193. PubMed PMID: 29170359. 2: Zhang L, Hao W, Xu L, Gao Y, Wang X, Zhu D, Chen Z, Zhang X, Chen H, Mei L. A pH-sensitive methenamine mandelate-loaded nanoparticle induces DNA damage and apoptosis of cancer cells. Acta Biomater. 2017 Oct 15;62:246-256. doi: 10.1016/j.actbio.2017.08.019. Epub 2017 Aug 16. PubMed PMID: 28822844. 3: Yang M, Tang Y. [Application of three methods of periodic acid-silver-methenamine staining in renal biopsy]. Zhonghua Bing Li Xue Za Zhi. 2017 Jun 8;46(6):419-420. doi: 10.3760/cma.j.issn.0529-5807.2017.06.013. Chinese. PubMed PMID: 28591993. 4: Lo TS, Hammer KD, Zegarra M, Cho WC. Methenamine: a forgotten drug for preventing recurrent urinary tract infection in a multidrug resistance era. Expert Rev Anti Infect Ther. 2014 May;12(5):549-54. doi: 10.1586/14787210.2014.904202. Epub 2014 Apr 1. Review. PubMed PMID: 24689705.