Synonym
Octodrine; SKF 51; SKF-51; SKF51.
IUPAC/Chemical Name
2-Heptanamine, 6-methyl-
InChi Key
QNIVIMYXGGFTAK-UHFFFAOYSA-N
InChi Code
InChI=1S/C8H19N/c1-7(2)5-4-6-8(3)9/h7-8H,4-6,9H2,1-3H3
SMILES Code
CC(N)CCCC(C)C
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Preparing Stock Solutions
The following data is based on the
product
molecular weight
129.25
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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2: Wang M, Haider S, Chittiboyina AG, Parcher JF, Khan IA. 1,5-Dimethylhexylamine (octodrine) in sports and weight loss supplements: Natural constituent or synthetic chemical? J Pharm Biomed Anal. 2018 Apr 15;152:298-305. doi: 10.1016/j.jpba.2018.02.008. Epub 2018 Feb 8. PubMed PMID: 29454882.
3: Cohen PA, Travis JC, Keizers PHJ, Deuster P, Venhuis BJ. Four experimental stimulants found in sports and weight loss supplements: 2-amino-6-methylheptane (octodrine), 1,4-dimethylamylamine (1,4-DMAA), 1,3-dimethylamylamine (1,3-DMAA) and 1,3-dimethylbutylamine (1,3-DMBA). Clin Toxicol (Phila). 2018 Jun;56(6):421-426. doi: 10.1080/15563650.2017.1398328. Epub 2017 Nov 8. PubMed PMID: 29115866.
4: Kim K, Zilbermintz L, Martchenko M. Repurposing FDA approved drugs against the human fungal pathogen, Candida albicans. Ann Clin Microbiol Antimicrob. 2015 Jun 9;14:32. doi: 10.1186/s12941-015-0090-4. PubMed PMID: 26054754; PubMed Central PMCID: PMC4462072.
5: Niu H, Cui P, Shi W, Zhang S, Feng J, Wang Y, Sullivan D, Zhang W, Zhu B, Zhang Y. Identification of Anti-Persister Activity against Uropathogenic Escherichia coli from a Clinical Drug Library. Antibiotics (Basel). 2015 May 12;4(2):179-87. doi: 10.3390/antibiotics4020179. PubMed PMID: 27025620; PubMed Central PMCID: PMC4790332.
6: Craciunescu DG, Doadrio A, Furlani A, Scarcia V. Structure-antitumour activity relationships for new platinum complexes. Chem Biol Interact. 1982 Nov;42(2):153-64. PubMed PMID: 6891293.
