MedKoo Cat#: 564028 | Name: MDK-2275
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

MDK-2275, also known as Pim1/AKK1-IN-1, is a potent multi-kinase inhibitor, targeting Pim1, AKK1, MST2, LKB1, MPSK1, and TNIK. MDK-2275 has CAS#1093222-27-5. Currently there is no formal or code name for this molecule. For the convenience of scientific communication, we temporally name it as MDK-2275.

Chemical Structure

MDK-2275
MDK-2275
CAS#1093222-27-5

Theoretical Analysis

MedKoo Cat#: 564028

Name: MDK-2275

CAS#: 1093222-27-5

Chemical Formula: C20H13N5O

Exact Mass: 339.1120

Molecular Weight: 339.36

Elemental Analysis: C, 70.79; H, 3.86; N, 20.64; O, 4.71

Price and Availability

Size Price Availability Quantity
500mg USD 2,450.00 2 weeks
1g USD 3,650.00 2 weeks
2g USD 5,850.00 2 weeks
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Related CAS #
No Data
Synonym
LKB1/AAK1 dual inhibitor; MDK-2275; MDK 2275; MDK2275;
IUPAC/Chemical Name
N-[5-(4-Cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-3-pyridinecarboxamide
InChi Key
JTSLALYXYSRPGW-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H13N5O/c21-9-13-3-5-14(6-4-13)16-8-17-18(12-24-19(17)23-11-16)25-20(26)15-2-1-7-22-10-15/h1-8,10-12H,(H,23,24)(H,25,26)
SMILES Code
O=C(C1=CC=CN=C1)NC2=CNC3=NC=C(C4=CC=C(C#N)C=C4)C=C32
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 339.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL