U 78753E | 67450-78-6 | xxxx

MedKoo Cat#: 581305 | Name: U 78753E

Description:

WARNING: This product is for research use only, not for human or veterinary use.

U 78753E is a biochemical.

Chemical Structure

U 78753E

CAS#67450-78-6

Theoretical Analysis

MedKoo Cat#: 581305

Name: U 78753E

CAS#: 67450-78-6

Chemical Formula: C16H22Cl2N2O

Exact Mass: 328.1109

Molecular Weight: 329.27

Elemental Analysis: Chemical Formula: C16H22Cl2N2O Exact Mass: 328.1109 Molecular Weight: 329.2650 Elemental Analysis: C, 58.37; H, 6.74; Cl, 21.53; N, 8.51; O, 4.86

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

U 78753E; DCDPP; U-78753E; U-78753E;

IUPAC/Chemical Name

N-(2-(Dimethylamino)cyclopentyl)-N-(3,4-dichlorophenyl)propanamid

InChi Key

YCRFSKUCDBJWLX-UHFFFAOYSA-N

InChi Code

InChI=1S/C16H22Cl2N2O/c1-4-16(21)20(11-8-9-12(17)13(18)10-11)15-7-5-6-14(15)19(2)3/h8-10,14-15H,4-7H2,1-3H3

SMILES Code

CCC(N(C1C(N(C)C)CCC1)C2=CC=C(Cl)C(Cl)=C2)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 329.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Aaron CS, Stankowski LF Jr, Harbach PR, Valencia R, Mayo JK, Mirsalis J, Mazurek JH, Steinmetz KL, Wiser SK, Zimmer DM, et al. Comparative mutagenicity testing of a drug candidate, U-48753E: mechanism of induction of gene mutations in mammalian cells and quantitation of potential hazard. Mutat Res. 1989 Jun;223(2):111-20. PubMed PMID: 2500592. 2: Sethy VH, Day JS, Cooper MM. Dose-dependent down-regulation of beta-adrenergic receptors after chronic intravenous infusion of antidepressants. Prog Neuropsychopharmacol Biol Psychiatry. 1988;12(5):673-82. PubMed PMID: 2851860. 3: Theis DL, Halstead GW, Capponi VJ, Roach BL, Robins RH. Quantitative determination of N-[trans-2-(dimethylamino)-cyclopentyl]-N-(3',4'-dichlorophenyl)propan amide, its 2H5-labeled analogue and their N-dealkylated metabolites in dog serum by capillary gas chromatography-mass spectrometry. J Chromatogr. 1986 Mar 7;375(2):299-311. PubMed PMID: 3700555. 4: Lakings DB, Stryd RP, Gilbertson TJ. Quantitative determination of N-(trans-2-dimethylaminocyclopentyl)-N-(3',4'-dichlorophenyl) propanamide and its N-demethyl metabolite in dog serum by gas chromatography. J Pharm Sci. 1984 Mar;73(3):317-20. PubMed PMID: 6716237. 5: Szmuszkovicz J, Von Voigtlander PF, Kane MP. A new nontricyclic antidepressant agent. Synthesis and activity of N-[trans-2-(dimethylamino)cyclopentyl]-N-(3,4-dichlorophenyl)propanamide and related compounds. J Med Chem. 1981 Oct;24(10):1230-6. PubMed PMID: 7328583.