BAY-846 is an allosteric MEK inhibitor with long half-lives, high bioavailabilities, low brain penetration potential and high efficacy in a K-Ras-mutated A549 xenograft model.
MedKoo Cat#: 563841
Name: BAY-846
CAS#: 1836185-18-2
Chemical Formula: C19H13F4IN4O4S
Exact Mass: 595.9638
Molecular Weight: 596.30
Elemental Analysis: C, 38.27; H, 2.20; F, 12.74; I, 21.28; N, 9.40; O, 10.73; S, 5.38
The following data is based on the product molecular weight 596.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
