TM-1 is an inhibitor of PDK1. TM-1 dose-dependently reduces phosphorylation of pyruvate dehydrogenase complex in MG-63 osteosarcoma cells and it inhibits the proliferation of MG-63 cells.
MedKoo Cat#: 563834
Name: TM-1
CAS#: 921099-13-0 (free base)
Chemical Formula: C26H32N2O6
Exact Mass: 468.2260
Molecular Weight: 468.55
Elemental Analysis: C, 66.65; H, 6.88; N, 5.98; O, 20.49
The following data is based on the product molecular weight 468.55 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
