MedKoo Cat#: 572674 | Name: RUN92619
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

RUN92619, also known as 4-amino-N-(4-(2-cyanoethynyl)phenyl)butanamide is part of a new class of thiol-specific conjugation reagents consisting of a thiol-reactive 3-arylpropiolonitrile (APN) group. The APN group allows the targeted coupling of thiols in biomolecules, and results in stable thioether linkages without the risk of subsequent side reactions that can occur with maleimides. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Chemical Structure

RUN92619
RUN92619
CAS#1539292-61-9

Theoretical Analysis

MedKoo Cat#: 572674

Name: RUN92619

CAS#: 1539292-61-9

Chemical Formula: C13H13N3O

Exact Mass: 227.1059

Molecular Weight: 227.27

Elemental Analysis: C, 68.70; H, 5.77; N, 18.49; O, 7.04

Price and Availability

Size Price Availability Quantity
25mg USD 450.00 2 Weeks
100mg USD 950.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
4-amino-N-(4-(2-cyanoethynyl)phenyl)butanamide; RUN 92619; RUN-92619; RUN92619
IUPAC/Chemical Name
4-amino-N-(4-(2-cyanoethynyl)phenyl)butanamide
InChi Key
RLTVJTXRTMTNBC-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H13N3O/c14-9-1-3-11-5-7-12(8-6-11)16-13(17)4-2-10-15/h5-8H,2,4,10,15H2,(H,16,17)
SMILES Code
O=C(NC1=CC=C(C#CC#N)C=C1)CCCN
Appearance
Solid powder
Purity
>97% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info
This product has good stability in aqueous media.

Preparing Stock Solutions

The following data is based on the product molecular weight 227.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Badescu G, Bryant P, Swierkosz J, Khayrzad F, Pawlisz E, Farys M, Cong Y, Muroni M, Rumpf N, Brocchini S, Godwin A. A new reagent for stable thiol-specific conjugation. Bioconjug Chem. 2014 Mar 19;25(3):460-9. doi: 10.1021/bc400245v. Epub 2014 Feb 11. PubMed PMID: 24512057.