NOSO-95179 | CAS#

MedKoo Cat#: 555303 | Name: NOSO-95179

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NOSO-95179 is an antibacterial compound that bind to the bacterial ribosome and kill bacteria through inhibition of the translation. NOSO-95C showed promising in vitro and in vivo efficacy against Enterobacteriaceae.

Chemical Structure

NOSO-95179

CAS#Unknown

Theoretical Analysis

MedKoo Cat#: 555303

Name: NOSO-95179

CAS#: Unknown

Chemical Formula: C44H77N17O11

Exact Mass: 1019.5988

Molecular Weight: 1020.21

Elemental Analysis: C, 51.80; H, 7.61; N, 23.34; O, 17.25

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

NOSO-95179; NOSO 95179; NOSO95179;

IUPAC/Chemical Name

(Z)-7-amino-2-((S)-6-amino-2-((S)-2-((S)-1-((2R,8S,11S,14S)-14,18-diamino-11-((S)-2-amino-1-hydroxyethyl)-2-(3-aminopropyl)-8-methyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazaoctadecanoyl)pyrrolidine-2-carboxamido)-3-(1H-imidazol-5-yl)propanamido)hexanamido)-7-iminohept-2-enoic acid

InChi Key

IIMLLJVGYGUVQJ-JKSAVDOXSA-N

InChi Code

InChI=1S/C44H77N17O11/c1-25(55-42(69)36(33(62)21-48)60-38(65)27(49)10-4-6-16-45)37(64)53-23-35(63)56-29(13-8-18-47)43(70)61-19-9-14-32(61)41(68)59-31(20-26-22-52-24-54-26)40(67)57-28(11-5-7-17-46)39(66)58-30(44(71)72)12-2-3-15-34(50)51/h12,22,24-25,27-29,31-33,36,62H,2-11,13-21,23,45-49H2,1H3,(H3,50,51)(H,52,54)(H,53,64)(H,55,69)(H,56,63)(H,57,67)(H,58,66)(H,59,68)(H,60,65)(H,71,72)/b30-12-/t25-,27-,28-,29+,31-,32-,33-,36-/m0/s1

SMILES Code

N[C@@H](CCCCN)C(N[C@@H]([C@@H](O)CN)C(N[C@@H](C)C(NCC(N[C@H](CCCN)C(N1[C@H](C(N[C@@H](CC2=CN=CN2)C(N[C@@H](CCCCN)C(N/C(C(O)=O)=C\CCCC(N)=N)=O)=O)=O)CCC1)=O)=O)=O)=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 1,020.21 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Sarciaux M, Pantel L, Midrier C, Serri M, Gerber C, de Figueiredo RM, Campagne JM, Villain-Guillot P, Gualtieri M, Racine E. Total Synthesis and Structure-Activity Relationships Study of Odilorhabdins, a New Class of Peptides Showing Potent Antibacterial Activity. J Med Chem. 2018 Aug 7. doi: 10.1021/acs.jmedchem.8b00790. [Epub ahead of print] PubMed PMID: 30086230