Propionic acid | CAS#79-09-4 | intermediate

MedKoo Cat#: 558660 | Name: Propionic acid

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Propionic acid serves as a preservative for animal feed and food for human consumption. It is a intermediate in the production of polymers including cellulose-acetate-propionate, artificial flavorings, agrochemicals and in bleaching agents

Chemical Structure

Propionic acid

CAS#79-09-4

Theoretical Analysis

MedKoo Cat#: 558660

Name: Propionic acid

CAS#: 79-09-4

Chemical Formula: C3H6O2

Exact Mass: 74.0400

Molecular Weight: 74.08

Elemental Analysis: C, 48.64; H, 8.16; O, 43.19

Price and Availability

Size	Price	Availability	Quantity
100g	USD 200.00
1kg	USD 310.00
2.5kg	USD 490.00

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Related CAS #

No Data

Synonym

Propionic acid; Metacetonic acid; Methyl acetic acid; Methylacetic acid;

IUPAC/Chemical Name

Propanoic acid

InChi Key

XBDQKXXYIPTUBI-UHFFFAOYSA-N

InChi Code

InChI=1S/C3H6O2/c1-2-3(4)5/h2H2,1H3,(H,4,5)

SMILES Code

CCC(O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 74.08 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Wang Z, Jin Y, Yang ST. High cell density propionic acid fermentation with an acid tolerant strain of Propionibacterium acidipropionici. Biotechnol Bioeng. 2015 Mar;112(3):502-11. doi: 10.1002/bit.25466. Epub 2014 Oct 21. PubMed PMID: 25257628. 2: González-Fandos E, Maya N, Pérez-Arnedo I. Effect of propionic acid on Campylobacter jejuni attached to chicken skin during refrigerated storage. Int Microbiol. 2015 Sep;18(3):171-5. doi: 10.2436/20.1501.01.247. PubMed PMID: 27036744. 3: Wang P, Jiao Y, Liu S. Novel fermentation process strengthening strategy for production of propionic acid and vitamin B12 by Propionibacterium freudenreichii. J Ind Microbiol Biotechnol. 2014 Dec;41(12):1811-5. doi: 10.1007/s10295-014-1513-5. Epub 2014 Sep 28. PubMed PMID: 25261985. 4: Stocks SE, Allen MS. Effects of lipid and propionic acid infusions on feed intake of lactating dairy cows. J Dairy Sci. 2014;97(4):2297-304. doi: 10.3168/jds.2013-7066. Epub 2014 Feb 15. PubMed PMID: 24534511. 5: Chen Y, Li X, Zheng X, Wang D. Enhancement of propionic acid fraction in volatile fatty acids produced from sludge fermentation by the use of food waste and Propionibacterium acidipropionici. Water Res. 2013 Feb 1;47(2):615-22. doi: 10.1016/j.watres.2012.10.035. Epub 2012 Oct 29. PubMed PMID: 23219005. 6: Zhang J, Guo G, Chen L, Li J, Yuan X, Yu C, Shimojo M, Shao T. Effect of applying lactic acid bacteria and propionic acid on fermentation quality and aerobic stability of oats-common vetch mixed silage on the Tibetan plateau. Anim Sci J. 2015 Jun;86(6):595-602. doi: 10.1111/asj.12340. Epub 2014 Dec 11. PubMed PMID: 25494579. 7: Wang Z, Ammar EM, Zhang A, Wang L, Lin M, Yang ST. Engineering Propionibacterium freudenreichii subsp. shermanii for enhanced propionic acid fermentation: effects of overexpressing propionyl-CoA:Succinate CoA transferase. Metab Eng. 2015 Jan;27:46-56. doi: 10.1016/j.ymben.2014.10.005. Epub 2014 Oct 29. PubMed PMID: 25447642. 8: Xu J, Bao JW, Su XF, Zhang HJ, Zeng X, Tang L, Wang K, Zhang JH, Chen XS, Mao ZG. Effect of propionic acid on citric acid fermentation in an integrated citric acid-methane fermentation process. Bioprocess Biosyst Eng. 2016 Mar;39(3):391-400. doi: 10.1007/s00449-015-1522-4. Epub 2015 Dec 12. PubMed PMID: 26658985. 9: Stocks SE, Allen MS. Hypophagic effects of propionic acid are not attenuated during a 3-day infusion in the early postpartum period in Holstein cows. J Dairy Sci. 2013 Jul;96(7):4615-23. doi: 10.3168/jds.2013-6653. Epub 2013 May 16. PubMed PMID: 23684018. 10: Wang P, Zhang Z, Jiao Y, Liu S, Wang Y. Improved propionic acid and 5,6-dimethylbenzimidazole control strategy for vitamin B12 fermentation by Propionibacterium freudenreichii. J Biotechnol. 2015 Jan 10;193:123-9. doi: 10.1016/j.jbiotec.2014.11.019. Epub 2014 Nov 29. PubMed PMID: 25455014. 11: Zhang A, Sun J, Wang Z, Yang ST, Zhou H. Effects of carbon dioxide on cell growth and propionic acid production from glycerol and glucose by Propionibacterium acidipropionici. Bioresour Technol. 2015 Jan;175:374-81. doi: 10.1016/j.biortech.2014.10.046. Epub 2014 Oct 22. PubMed PMID: 25459845. 12: Dishisha T, Ibrahim MH, Cavero VH, Alvarez MT, Hatti-Kaul R. Improved propionic acid production from glycerol: combining cyclic batch- and sequential batch fermentations with optimal nutrient composition. Bioresour Technol. 2015 Jan;176:80-7. doi: 10.1016/j.biortech.2014.11.013. Epub 2014 Nov 11. PubMed PMID: 25460987. 13: Sabra W, Dietz D, Zeng AP. Substrate-limited co-culture for efficient production of propionic acid from flour hydrolysate. Appl Microbiol Biotechnol. 2013 Jul;97(13):5771-7. doi: 10.1007/s00253-013-4913-y. Epub 2013 May 1. PubMed PMID: 23636693. 14: Wang Z, Yang ST. Propionic acid production in glycerol/glucose co-fermentation by Propionibacterium freudenreichii subsp. shermanii. Bioresour Technol. 2013 Jun;137:116-23. doi: 10.1016/j.biortech.2013.03.012. Epub 2013 Mar 14. PubMed PMID: 23584412. 15: Catenazzi MC, Jones H, Wallace I, Clifton J, Chong JP, Jackson MA, Macdonald S, Edwards J, Moir JW. A large genomic island allows Neisseria meningitidis to utilize propionic acid, with implications for colonization of the human nasopharynx. Mol Microbiol. 2014 Jul;93(2):346-55. doi: 10.1111/mmi.12664. Epub 2014 Jun 27. PubMed PMID: 24910087; PubMed Central PMCID: PMC4441257. 16: Kämpf MM, Thöny-Meyer L, Ren Q. Biosynthesis of poly(4-hydroxybutyrate) in recombinant Escherichia coli grown on glycerol is stimulated by propionic acid. Int J Biol Macromol. 2014 Nov;71:8-13. doi: 10.1016/j.ijbiomac.2014.04.023. Epub 2014 Apr 23. PubMed PMID: 24769215. 17: Chen L, Guo G, Yuan X, Zhang J, Li J, Shao T. Effects of applying molasses, lactic acid bacteria and propionic acid on fermentation quality, aerobic stability and in vitro gas production of total mixed ration silage prepared with oat-common vetch intercrop on the Tibetan Plateau. J Sci Food Agric. 2016 Mar 30;96(5):1678-85. doi: 10.1002/jsfa.7271. Epub 2015 Jun 19. PubMed PMID: 25996908. 18: Chen F, Feng XH, Liang JF, Xu H, Ouyang PK. An oxidoreduction potential shift control strategy for high purity propionic acid production by Propionibacterium freudenreichii CCTCC M207015 with glycerol as sole carbon source. Bioprocess Biosyst Eng. 2013 Sep;36(9):1165-76. doi: 10.1007/s00449-012-0843-9. Epub 2012 Oct 30. PubMed PMID: 23108441. 19: Ammar EM, Jin Y, Wang Z, Yang ST. Metabolic engineering of Propionibacterium freudenreichii: effect of expressing phosphoenolpyruvate carboxylase on propionic acid production. Appl Microbiol Biotechnol. 2014 Sep;98(18):7761-72. doi: 10.1007/s00253-014-5836-y. Epub 2014 May 31. PubMed PMID: 24878752. 20: Dishisha T, Ståhl Å, Lundmark S, Hatti-Kaul R. An economical biorefinery process for propionic acid production from glycerol and potato juice using high cell density fermentation. Bioresour Technol. 2013 May;135:504-12. doi: 10.1016/j.biortech.2012.08.098. Epub 2012 Aug 31. PubMed PMID: 23041117.