MedKoo Cat#: 592913 | Name: Todralazine hydrochloride
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Todralazine hydrochloride is an antihypertensive agent with both central and peripheral action; it has some central nervous system depressant effects.

Chemical Structure

Todralazine hydrochloride
CAS#3778-76-5 (HCl)

Theoretical Analysis

MedKoo Cat#: 592913

Name: Todralazine hydrochloride

CAS#: 3778-76-5 (HCl)

Chemical Formula: C11H13ClN4O2

Exact Mass: 268.0727

Molecular Weight: 268.70

Elemental Analysis: C, 49.17; H, 4.88; Cl, 13.19; N, 20.85; O, 11.91

Price and Availability

Size Price Availability Quantity
100mg USD 450.00 2 Weeks
200mg USD 750.00 2 Weeks
500mg USD 1,650.00 2 Weeks
1g USD 2,950.00 2 Weeks
2g USD 5,250.00 2 Weeks
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Related CAS #
3778-76-5 (HCl) 14679-73-3 (free base)
Synonym
Todralazine hydrochloride; Todralazine HCl; Todralazine (HCl);
IUPAC/Chemical Name
Carbazic acid, 3-(1-phthalazinyl)-, ethyl ester, monohydrochloride
InChi Key
OMCOKCNIYWULQH-UHFFFAOYSA-N
InChi Code
InChI=1S/C11H12N4O2.ClH/c1-2-17-11(16)15-14-10-9-6-4-3-5-8(9)7-12-13-10;/h3-7H,2H2,1H3,(H,13,14)(H,15,16);1H
SMILES Code
O=C(OCC)NNC1=NN=CC2=C1C=CC=C2.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 268.70 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Tameda Y, Hamada M, Takase K, Nakano T, Kosaka Y. Fulminant hepatic failure caused by ecarazine hydrochloride (a hydralazine derivative). Hepatology. 1996 Mar;23(3):465-70. PubMed PMID: 8617425. 2: Ishii A, Kubo K, Deguchi T, Tanaka M. [Inhibition of cyclic AMP phosphodiesterase activity by ecarazine hydrochloride, hydralazine and their metabolites (author's transl)]. Yakugaku Zasshi. 1979 May;99(5):533-6. Japanese. PubMed PMID: 232515.