Losindole | CAS#69175-77-5 | antidepressant

MedKoo Cat#: 599247 | Name: Losindole

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Losindole is an antidepressant with a tetracyclic structure.

Chemical Structure

Losindole

CAS#69175-77-5

Theoretical Analysis

MedKoo Cat#: 599247

Name: Losindole

CAS#: 69175-77-5

Chemical Formula: C19H20ClN

Exact Mass: 297.1284

Molecular Weight: 297.82

Elemental Analysis: C, 76.62; H, 6.77; Cl, 11.90; N, 4.70

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Losindole;

IUPAC/Chemical Name

(3aS,4R,9aR)-6-chloro-2-methyl-4-phenyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]isoindole

InChi Key

ZHKXDUQRKZQCQV-KFKAGJAMSA-N

InChi Code

InChI=1S/C19H20ClN/c1-21-11-15-9-14-7-8-16(20)10-17(14)19(18(15)12-21)13-5-3-2-4-6-13/h2-8,10,15,18-19H,9,11-12H2,1H3/t15-,18+,19+/m0/s1

SMILES Code

CN1C[C@]2([H])CC3=CC=C(Cl)C=C3[C@@H](C4=CC=CC=C4)[C@]2([H])C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 297.82 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Sweat F, Puchtler H, Terry MS. Staining isolated proteins and polysaccharides on slides; phosphotungstic acid-hematoxylin versus the rosindole reaction. Stain Technol. 1968 Sep;43(5):283-6. PubMed PMID: 4176666. 2: PUCHTLER H, CHANDLER AB, SWEAT F. Demonstration of fibrin in tissue sections by the Rosindole method. J Histochem Cytochem. 1961 May;9:340-1. PubMed PMID: 14489116. 3: Kingsbury AN, Kanagarayer K. On the Technique and Significance of the Rosindole Reaction, Applied to Urine. Ind Med Gaz. 1925 Apr;60(4):161-163. PubMed PMID: 29010352; PubMed Central PMCID: PMC5188941. 4: GLENNER GG. The histochemical demonstration of indole derivatives by the rosindole reaction of E. Fischer. J Histochem Cytochem. 1957 May;5(3):297-304. PubMed PMID: 13449315. 5: Katayama I, Higashi K, Mukai H, Nishioka K, Nishiyama S. Tumoral calcinosis in scleroderma. J Dermatol. 1989 Feb;16(1):82-5. PubMed PMID: 2470801.