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MedKoo Cat#: 471007 | Name: Ciclopirox Olamine
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ciclopirox olamine is a synthetic, broad-spectrum antifungal agent with additional antibacterial, anti-inflammatory and also recently antitumor activities.

Chemical Structure

Ciclopirox Olamine
Ciclopirox Olamine
CAS#41621-49-2 (olamine)

Theoretical Analysis

MedKoo Cat#: 471007

Name: Ciclopirox Olamine

CAS#: 41621-49-2 (olamine)

Chemical Formula: C14H24N2O3

Exact Mass: 0.0000

Molecular Weight: 268.36

Elemental Analysis: C, 62.66; H, 9.01; N, 10.44; O, 17.89

Price and Availability

Size Price Availability Quantity
5g USD 250.00 2 Weeks
25g USD 550.00 2 Weeks
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Related CAS #
41621-49-2 (olamine) 29342-05-0 (free)
Synonym
Ciclopirox Olamine; Ciclopirox Ethanolamine
IUPAC/Chemical Name
6-cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one compound with 2-aminoethan-1-ol
InChi Key
MBRHNTMUYWQHMR-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H17NO2.C2H7NO/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10;3-1-2-4/h7-8,10,15H,2-6H2,1H3;4H,1-3H2
SMILES Code
O=C1C=C(C)C=C(C2CCCCC2)N1O.NCCO
Appearance
Solid powder
Purity
>97% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 268.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Ciclopirox: an overview. A. K. Gupta, Int. J. Dermatol. 2001, 40, 305. 2. Ciclopirox: recent nonclinical and clinical data relevant to its use as a topical antimycotic agent. A. Subissi, D. Monti, G. Togni, F. Mailland, Drugs 2010, 70, 2133. 3. Chelation of intracellular iron with the antifungal agent ciclopirox olamine induces cell death in leukemia and myeloma cells. Y. Eberhard, S. P. McDermott, X. Wang, M. Gronda, A. Venugopal, T. E. Wood, R. Hurren, A. Datti, R. A. Batey, J. Wrana, W. E. Antholine, J. E. Dick, A. D. Schimmer, Blood 2009, 114, 3064. 4. The antitumor activity of the fungicide ciclopirox. H. Zhou, T. Shen, Y. Luo, L. Liu, W. Chen, B. Xu, X. Han, J. Pang, C. A. Rivera, S. Huang, Int. J. Cancer2010, 127, 2467. 5. The repositioning of the anti-fungal agent ciclopirox olamine as a novel therapeutic agent for the treatment of haematologic malignancy. S. J. Weir, L. Patton, K. Castle, L. Rajewski, J. Kasper, A. D. Schimmer, J. Clin. Pharm. Ther. 2011, 36, 128.