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MedKoo Cat#: 573526 | Name: Longifolin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Longifolin is an antigenotoxic chalcone glycoside from Mentha longifolia subsp. longifolia.

Chemical Structure

Longifolin
Longifolin
CAS#39007-94-8

Theoretical Analysis

MedKoo Cat#: 573526

Name: Longifolin

CAS#: 39007-94-8

Chemical Formula: C15H18O2

Exact Mass: 230.1307

Molecular Weight: 230.30

Elemental Analysis: C, 78.23; H, 7.88; O, 13.89

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Longifolin;
IUPAC/Chemical Name
(E)-3-methyl-2-(3-methyl-4-(4-methylfuran-2-yl)but-2-en-1-yl)furan
InChi Key
KATZGWUZXSGURX-NYYWCZLTSA-N
InChi Code
InChI=1S/C15H18O2/c1-11(8-14-9-12(2)10-17-14)4-5-15-13(3)6-7-16-15/h4,6-7,9-10H,5,8H2,1-3H3/b11-4+
SMILES Code
CC1=COC(C/C(C)=C/CC2=C(C)C=CO2)=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 230.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Han YM, Kim IS, Rehman SU, Choe K, Yoo HH. In Vitro Evaluation of the Effects of Eurycoma longifolia Extract on CYP-Mediated Drug Metabolism. Evid Based Complement Alternat Med. 2015;2015:631329. doi: 10.1155/2015/631329. Epub 2015 Jul 9. PubMed PMID: 26240600; PubMed Central PMCID: PMC4512589. 2: Guvenalp Z, Ozbek H, Karadayi M, Gulluce M, Kuruuzum-Uz A, Salih B, Demirezer O. Two antigenotoxic chalcone glycosides from Mentha longifolia subsp. longifolia. Pharm Biol. 2015 Jun;53(6):888-96. doi: 10.3109/13880209.2014.948633. Epub 2014 Nov 28. PubMed PMID: 25429992. 3: Zaini NN, Osman R, Juahir H, Saim N. Development of Chromatographic Fingerprints of Eurycoma longifolia (Tongkat Ali) Roots Using Online Solid Phase Extraction-Liquid Chromatography (SPE-LC). Molecules. 2016 Apr 30;21(5). pii: E583. doi: 10.3390/molecules21050583. PubMed PMID: 27144555. 4: Jothy SL, Saito T, Kanwar JR, Chen Y, Aziz A, Yin-Hui L, Sasidharan S. Radioprotective activity of Polyalthia longifolia standardized extract against X-ray radiation injury in mice. Phys Med. 2016 Jan;32(1):150-61. doi: 10.1016/j.ejmp.2015.10.090. Epub 2015 Oct 30. PubMed PMID: 26526749. 5: Rehman SU, Choe K, Yoo HH. Review on a Traditional Herbal Medicine, Eurycoma longifolia Jack (Tongkat Ali): Its Traditional Uses, Chemistry, Evidence-Based Pharmacology and Toxicology. Molecules. 2016 Mar 10;21(3):331. doi: 10.3390/molecules21030331. Review. PubMed PMID: 26978330. 6: Kotirum S, Ismail SB, Chaiyakunapruk N. Efficacy of Tongkat Ali (Eurycoma longifolia) on erectile function improvement: systematic review and meta-analysis of randomized controlled trials. Complement Ther Med. 2015 Oct;23(5):693-8. doi: 10.1016/j.ctim.2015.07.009. Epub 2015 Jul 31. Review. PubMed PMID: 26365449. 7: George A, Henkel R. Phytoandrogenic properties of Eurycoma longifolia as natural alternative to testosterone replacement therapy. Andrologia. 2014 Sep;46(7):708-21. doi: 10.1111/and.12214. Epub 2014 Jan 6. Review. PubMed PMID: 24386995. 8: Jalilzadeh-Amin G, Maham M. Antidiarrheal activity and acute oral toxicity of Mentha longifolia L. essential oil. Avicenna J Phytomed. 2015 Mar-Apr;5(2):128-37. PubMed PMID: 25949954; PubMed Central PMCID: PMC4418062. 9: Moniruzzaman M, Ferdous A, Wahid Bokul F. Evaluation of antinociceptive activity of ethanol extract of bark of Polyalthia longifolia. J Ethnopharmacol. 2015 Aug 22;172:364-7. doi: 10.1016/j.jep.2015.06.053. Epub 2015 Jul 10. PubMed PMID: 26165827. 10: Chen Y, Phang WM, Mu AK, Chan CK, Low BS, Sasidharan S, Chan KL. Decreased expression of alpha-2-HS glycoprotein in the sera of rats treated with Eurycoma longifolia extract. Front Pharmacol. 2015 Sep 23;6:211. doi: 10.3389/fphar.2015.00211. eCollection 2015. PubMed PMID: 26441666; PubMed Central PMCID: PMC4585282. 11: Saeidi S, Hassanpour K, Ghamgosha M, Heiat M, Taheri RA, Mirhosseini A, Farnoosh G. Antibacterial activity of ethyl acetate and aqueous extracts of Mentha longifolia L. and hydroalcoholic extract of Zataria multiflora Boiss. plants against important human pathogens. Asian Pac J Trop Med. 2014 Sep;7S1:S186-9. doi: 10.1016/S1995-7645(14)60229-7. PubMed PMID: 25312118. 12: Tong KL, Chan KL, AbuBakar S, Low BS, Ma HQ, Wong PF. The in vitro and in vivo anti-cancer activities of a standardized quassinoids composition from Eurycoma longifolia on LNCaP human prostate cancer cells. PLoS One. 2015 Mar 31;10(3):e0121752. doi: 10.1371/journal.pone.0121752. eCollection 2015. PubMed PMID: 25826409; PubMed Central PMCID: PMC4380335. 13: Tran TV, Malainer C, Schwaiger S, Atanasov AG, Heiss EH, Dirsch VM, Stuppner H. NF-κB inhibitors from Eurycoma longifolia. J Nat Prod. 2014 Mar 28;77(3):483-8. doi: 10.1021/np400701k. Epub 2014 Jan 27. PubMed PMID: 24467387; PubMed Central PMCID: PMC3971761. 14: Cao CM, Kindscher K, Gallagher RJ, Zhang H, Timmermann BN. Analysis of Major Withanolides in Physalis longifolia Nutt. by HPLC-PDA. J Chromatogr Sci. 2015 Aug;53(7):1044-7. doi: 10.1093/chromsci/bmu162. Epub 2014 Dec 2. PubMed PMID: 25466231; PubMed Central PMCID: PMC4592342. 15: Gulluce M, Orhan F, Yanmis D, Arasoglu T, Guvenalp Z, Demirezer LO. Isolation of a flavonoid, apigenin 7-O-glucoside, from Mentha longifolia (L.) Hudson subspecies longifolia and its genotoxic potency. Toxicol Ind Health. 2015 Sep;31(9):831-40. doi: 10.1177/0748233713475511. Epub 2013 Feb 1. PubMed PMID: 23377117. 16: Khanijo T, Jiraungkoorskul W. Review Ergogenic Effect of Long Jack, Eurycoma Longifolia. Pharmacogn Rev. 2016 Jul-Dec;10(20):139-142. doi: 10.4103/0973-7847.194041. PubMed PMID: 28082797; PubMed Central PMCID: PMC5214558. 17: dos Santos AE, Kuster RM, Yamamoto KA, Salles TS, Campos R, de Meneses MD, Soares MR, Ferreira D. Quercetin and quercetin 3-O-glycosides from Bauhinia longifolia (Bong.) Steud. show anti-Mayaro virus activity. Parasit Vectors. 2014 Mar 28;7:130. doi: 10.1186/1756-3305-7-130. PubMed PMID: 24678592; PubMed Central PMCID: PMC3973022. 18: Chen XX, Liang G, Chai WM, Feng HL, Zhou HT, Shi Y, Chen QX. Antioxidant and antityrosinase proanthocyanidins from Polyalthia longifolia leaves. J Biosci Bioeng. 2014 Nov;118(5):583-7. doi: 10.1016/j.jbiosc.2014.04.015. Epub 2014 May 24. PubMed PMID: 24863181. 19: Chen CK, Mohamad WM, Ooi FK, Ismail SB, Abdullah MR, George A. Supplementation of Eurycoma longifolia Jack Extract for 6 Weeks Does Not Affect Urinary Testosterone: Epitestosterone Ratio, Liver and Renal Functions in Male Recreational Athletes. Int J Prev Med. 2014 Jun;5(6):728-33. PubMed PMID: 25013692; PubMed Central PMCID: PMC4085925. 20: Saeidnia S, Ara L, Hajimehdipoor H, Read RW, Arshadi S, Nikan M. Chemical constituents of Swertia longifolia Boiss. with α-amylase inhibitory activity. Res Pharm Sci. 2016 Jan-Feb;11(1):23-32. PubMed PMID: 27051429; PubMed Central PMCID: PMC4794934.

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Monohexyl phosphate

Monohexyl phosphate