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MedKoo Cat#: 599179 | Name: Lonetil M3

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lonetil M3 is a tranquilizer.

Chemical Structure

Lonetil M3
Lonetil M3
CAS#1897-96-7

Theoretical Analysis

MedKoo Cat#: 599179

Name: Lonetil M3

CAS#: 1897-96-7

Chemical Formula: C17H16N2O2

Exact Mass: 280.1212

Molecular Weight: 280.32

Elemental Analysis: C, 72.84; H, 5.75; N, 9.99; O, 11.41

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Lonetil M3; Lonethyl; Lonetil; B 146; B-146; B146;
IUPAC/Chemical Name
3-(4-ethoxyphenyl)-2-methylquinazolin-4(3H)-one
InChi Key
JKWBQCHTVBSJDC-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H16N2O2/c1-3-21-14-10-8-13(9-11-14)19-12(2)18-16-7-5-4-6-15(16)17(19)20/h4-11H,3H2,1-2H3
SMILES Code
O=C1N(C2=CC=C(OCC)C=C2)C(C)=NC3=C1C=CC=C3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 280.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Boiadzhieva N. [Experimental studies on the effect of Bulgarian anxiolytic lonetil on some endocrine functions]. Eksp Med Morfol. 1989;28(1):37-40. Bulgarian. PubMed PMID: 2568251. 2: Vlakhov V, Bakracheva N. [Effect of the preparations lonetil and adepren on local cerebral blood flow]. Eksp Med Morfol. 1983;22(2):84-7. Bulgarian. PubMed PMID: 6667660. 3: Danchev N, Val'dman A. [Lonetil and emovit--effect on an experimental model of a neurosis-like state in the rat]. Eksp Med Morfol. 1983;22(4):9-15. Bulgarian. PubMed PMID: 6143655. 4: Val'dman AV, Danchev ND. [Emovit and lonetil--behavioral and neurochemical studies]. Eksp Med Morfol. 1983;22(2):59-64. Bulgarian. PubMed PMID: 6321132. 5: Ovcharov R, Danchev N. [Interrelationship of the tranquilizers diazepam and lonetil with dopamine mediation in the central nervous system]. Eksp Med Morfol. 1981;20(2):88-96. Bulgarian. PubMed PMID: 7250025. 6: Voronina TA, Garibova TL. [Experimental study of the "'rebound syndrome" following discontinuation of prolonged phenazepam administration and possibilities for preventing it]. Zh Nevropatol Psikhiatr Im S S Korsakova. 1981;81(7):1056-9. Russian. PubMed PMID: 7197446. 7: Tsikalova R, Nikolova M, Nikolov R. The effect of lonetyl on the electroencephalogram and rheoencephalogram of experimental animals. Acta Physiol Pharmacol Bulg. 1981;7(4):43-8. PubMed PMID: 7345893. 8: Daleva L, Stefanova D. [Experimental models of anxiety as a method of predicting the tranquilizing effect of psychotropic drugs]. Eksp Med Morfol. 1982;21(1):33-8. Bulgarian. PubMed PMID: 7201380. 9: Khonicheva NM, Danchev N. [Development of passivity in the rat: effect of tranquilizers and antidepressants]. Zh Vyssh Nerv Deiat Im I P Pavlova. 1985 Mar-Apr;35(2):339-47. Russian. PubMed PMID: 4040687. 10: Anokhina IP, Iumatov EA, Ivanova TM, Skotselias IuG. [Concentration of biogenic amines in different brain structures of the rat adapted to chronic emotional stress]. Zh Vyssh Nerv Deiat Im I P Pavlova. 1985 Mar-Apr;35(2):348-53. Russian. PubMed PMID: 2411063.