Fungichromin | CAS#6834-98-6 | macrolide antibiotic

MedKoo Cat#: 461627 | Name: Fungichromin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Fungichromin, also known as pentamycin, is a polyene macrolide antibiotic produced by Streptomyces species, characterized by a large macrocyclic lactone ring with conjugated double bonds and multiple hydroxyl groups. It exerts antifungal activity by binding to ergosterol in fungal cell membranes, disrupting membrane integrity and causing ion leakage and cell death. Fungichromin shows selective toxicity toward fungal cells and is used in both agricultural and medical applications for controlling fungal infections.

Chemical Structure

Fungichromin

CAS#6834-98-6

Theoretical Analysis

MedKoo Cat#: 461627

Name: Fungichromin

CAS#: 6834-98-6

Chemical Formula: C35H58O12

Exact Mass: 670.3928

Molecular Weight: 670.83

Elemental Analysis: C, 62.67; H, 8.72; O, 28.62

Price and Availability

Size	Price	Availability	Quantity
10mg	USD 1,250.00	2 Weeks
25mg	USD 2,450.00	2 Weeks

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Related CAS #

6834-98-6

Synonym

Fungichromin; Cogomycin; Lagosin; Pentamycin; 14-hydroxy Filipin; NSC 105388; NSC105388; NSC-105388; NSC 276732; NSC276732; NSC-276732; S 232; S-232; S232;

IUPAC/Chemical Name

(3R,4S,6S,8S,10R,12R,14R,15R,16R,17E,19E,21E,23E,25E,27S,28R)-4,6,8,10,12,14,15,16,27-nonahydroxy-3-((R)-1-hydroxyhexyl)-17,28-dimethyloxacyclooctacosa-17,19,21,23,25-pentaen-2-one

InChi Key

AGJUUQSLGVCRQA-SWOUQTJZSA-N

InChi Code

InChI=1S/C35H58O12/c1-4-5-11-16-29(41)32-30(42)20-26(38)18-24(36)17-25(37)19-27(39)21-31(43)34(45)33(44)22(2)14-12-9-7-6-8-10-13-15-28(40)23(3)47-35(32)46/h6-10,12-15,23-34,36-45H,4-5,11,16-21H2,1-3H3/b7-6+,10-8+,12-9+,15-13+,22-14+/t23-,24+,25-,26+,27-,28+,29-,30+,31-,32-,33-,34-/m1/s1

SMILES Code

C/C1=C\C=C\C=C\C=C\C=C\[C@H](O)[C@@H](C)OC([C@H]([C@H](O)CCCCC)[C@@H](O)C[C@@H](O)C[C@@H](O)C[C@@H](O)C[C@@H](O)C[C@@H](O)[C@@H](O)[C@@H]1O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 670.83 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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