RX 809055AX | CAS#122566-12-5 | opioid antagonist

MedKoo Cat#: 461590 | Name: RX 809055AX

Description:

WARNING: This product is for research use only, not for human or veterinary use.

RX 809055AX is a long lasting opioid antagonist at mu and delta receptors.

Chemical Structure

RX 809055AX

CAS#122566-12-5

Theoretical Analysis

MedKoo Cat#: 461590

Name: RX 809055AX

CAS#: 122566-12-5

Chemical Formula: C29H29ClN2O4

Exact Mass: 504.1816

Molecular Weight: 505.01

Elemental Analysis: C, 68.97; H, 5.79; Cl, 7.02; N, 5.55; O, 12.67

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

RX 809055AX; RX-809055AX; RX809055AX;

IUPAC/Chemical Name

(E)-3-(4-chlorophenyl)-N-((4R,4aS,7aR,12bR)-3-(cyclopropylmethyl)-9-hydroxy-7-oxo-1,2,3,4,5,6,7,7a-octahydro-4aH-4,12-methanobenzofuro[3,2-e]isoquinolin-4a-yl)acrylamide

InChi Key

RAURUSFBVQLAPW-DNIKMYEQSA-N

InChi Code

InChI=1S/C29H29ClN2O4/c30-20-7-3-17(4-8-20)5-10-24(35)31-29-12-11-22(34)27-28(29)13-14-32(16-18-1-2-18)23(29)15-19-6-9-21(33)26(36-27)25(19)28/h3-10,18,23,27,33H,1-2,11-16H2,(H,31,35)/b10-5+/t23-,27+,28+,29-/m1/s1

SMILES Code

O=C(N[C@]1([C@]2([C@@]3([H])O4)C5=C4C(O)=CC=C5C[C@H]1N(CC6CC6)CC2)CCC3=O)/C=C/C7=CC=C(Cl)C=C7

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 505.01 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Davis P, Kramer T, Burks T. In vitro evaluation of a novel, non-competitive opioid receptor antagonist. Proc West Pharmacol Soc. 1989;32:163-6. PubMed PMID: 2550940. 2: Lemcke PK, Ayres EA, Kramer TH, Burks TF. RX809055AX in vivo: a long lasting opioid antagonist at mu and delta receptors. Proc West Pharmacol Soc. 1989;32:173-5. PubMed PMID: 2550942.