MedKoo Cat#: 461586 | Name: RX 67668

Description:

WARNING: This product is for research use only, not for human or veterinary use.

RX 67668 is an anticholinesterase drug.

Chemical Structure

RX 67668
RX 67668
CAS#40709-76-0

Theoretical Analysis

MedKoo Cat#: 461586

Name: RX 67668

CAS#: 40709-76-0

Chemical Formula: C16H24ClN

Exact Mass: 265.1597

Molecular Weight: 265.82

Elemental Analysis: C, 72.29; H, 9.10; Cl, 13.34; N, 5.27

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
RX 67668; RX-67668; RX67668;
IUPAC/Chemical Name
1-((1R,2R)-2-phenylcyclohexyl)pyrrolidine hydrochloride
InChi Key
PFJUKRASTDOAQF-QNBGGDODSA-N
InChi Code
InChI=1S/C16H23N.ClH/c1-2-8-14(9-3-1)15-10-4-5-11-16(15)17-12-6-7-13-17;/h1-3,8-9,15-16H,4-7,10-13H2;1H/t15-,16-;/m1./s1
SMILES Code
[H]Cl.[C@H]1(N2CCCC2)[C@@H](C3=CC=CC=C3)CCCC1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 265.82 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Doxey JC, Metcalf G, Smith MH, Whittle BA. Some pharmacological properties of RX 67668--a new anticholinesterase. Br J Pharmacol. 1972 Nov;46(3):568P-569P. PubMed PMID: 4656643; PubMed Central PMCID: PMC1666515. 2: Gillett GB, Hedges A, Metcalf G, Richens A, Royds RB. Reversal of competitive neuromuscular blockade by RX 67668 in normal volunteers. Br J Pharmacol. 1972 Nov;46(3):581P-582P. PubMed PMID: 4656654; PubMed Central PMCID: PMC1666490. 3: Turner P, Variava DM. Comparison of the potencies of edrophonium, neostigmine and eserine with a new anticholinesterase drug RX 67668 on human tissues. Br J Pharmacol. 1973 Mar;47(3):678P. PubMed PMID: 4730883; PubMed Central PMCID: PMC1776352.