Lithium guanosine triphosphate | CAS#85737-04-8 | carrier of phosphates

MedKoo Cat#: 599011 | Name: Lithium guanosine triphosphate

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lithium guanosine triphosphate functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. GTP activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of several intracellular kinase cascades. Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle formation. In addition to its role in signal transduction, GTP also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.

Chemical Structure

Lithium guanosine triphosphate

CAS#85737-04-8

Theoretical Analysis

MedKoo Cat#: 599011

Name: Lithium guanosine triphosphate

CAS#: 85737-04-8

Chemical Formula: C10H14Li2N5O14P3

Exact Mass:

Molecular Weight: 535.04

Elemental Analysis: C, 22.45; H, 2.64; Li, 2.59; N, 13.09; O, 41.86; P, 17.37

Price and Availability

Size	Price	Availability	Quantity
25mg	USD 300.00	2 Weeks
100mg	USD 700.00	2 Weeks

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Related CAS #

No Data

Synonym

Lithium guanosine triphosphate;

IUPAC/Chemical Name

lithium (2R,3R,4S,5R)-2-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-5-(((hydroxy((hydroxy(phosphonooxy)phosphoryl)oxy)phosphoryl)oxy)methyl)tetrahydrofuran-3,4-bis(olate)

InChi Key

JQAAFGBHTUYJSO-LGVAUZIVSA-N

InChi Code

InChI=1S/C10H14N5O14P3.2Li/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21;;/h2-3,5-6,9H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18);;/q-2;2*+1/t3-,5-,6-,9-;;/m1../s1

SMILES Code

[O-][C@@H]([C@H]([C@H](N1C=NC2=C1N=C(N)NC2=O)O3)[O-])[C@H]3COP(O)(OP(OP(O)(O)=O)(O)=O)=O.[Li+].[Li+]

Appearance

Solid powder

Purity

>95% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Product Data

Product Data

Instruction

View handling instruction

Biological target:

Lithium guanosine triphosphate functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways.

In vitro activity:

TBD

In vivo activity:

TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 535.04 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:

TBD

In vitro protocol:

TBD

In vivo protocol:

TBD

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