Linichlorin A | CAS#62462-98-0 | ubiquitination inhibitor

MedKoo Cat#: 598927 | Name: Linichlorin A

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Linichlorin A is a p27(Kip1) ubiquitination inhibitor.

Chemical Structure

Linichlorin A

CAS#62462-98-0

Theoretical Analysis

MedKoo Cat#: 598927

Name: Linichlorin A

CAS#: 62462-98-0

Chemical Formula: C19H23ClO6

Exact Mass: 382.1183

Molecular Weight: 382.83

Elemental Analysis: C, 59.61; H, 6.06; Cl, 9.26; O, 25.07

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Linichlorin A; Elegin;

IUPAC/Chemical Name

(3aR,4S,6aR,8S,9S,9aR,9bS)-9-(chloromethyl)-8,9-dihydroxy-3,6-dimethylene-2-oxododecahydroazuleno[4,5-b]furan-4-yl methacrylate

InChi Key

ONMAQPPVCANFPB-HBMVKAIRSA-N

InChi Code

InChI=1S/C19H23ClO6/c1-8(2)17(22)25-12-5-9(3)11-6-13(21)19(24,7-20)15(11)16-14(12)10(4)18(23)26-16/h11-16,21,24H,1,3-7H2,2H3/t11-,12-,13-,14+,15+,16-,19+/m0/s1

SMILES Code

C=C(C)C(O[C@H]1CC([C@@H]2C[C@H](O)[C@](O)(CCl)[C@H]2[C@H]3OC(C([C@H]13)=C)=O)=C)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 382.83 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Ooi LC, Watanabe N, Futamura Y, Sulaiman SF, Darah I, Osada H. Identification of small molecule inhibitors of p27(Kip1) ubiquitination by high-throughput screening. Cancer Sci. 2013 Nov;104(11):1461-7. doi: 10.1111/cas.12246. Epub 2013 Sep 6. PubMed PMID: 23910095. 2: Farmer KW, Wright TW. Shoulder arthroscopy: the basics. J Hand Surg Am. 2015 Apr;40(4):817-21. doi: 10.1016/j.jhsa.2015.01.002. Epub 2015 Feb 26. Review. PubMed PMID: 25726045.