MedKoo Cat#: 598909 | Name: Linatine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Linatine is a bacterial inhibitor.

Chemical Structure

Linatine
Linatine
CAS#10139-06-7

Theoretical Analysis

MedKoo Cat#: 598909

Name: Linatine

CAS#: 10139-06-7

Chemical Formula: C10H17N3O5

Exact Mass: 259.1168

Molecular Weight: 259.26

Elemental Analysis: C, 46.33; H, 6.61; N, 16.21; O, 30.85

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Linatine;
IUPAC/Chemical Name
((S)-4-amino-4-carboxybutanamido)-D-proline
InChi Key
KWWHDNLMGLRNRN-NKWVEPMBSA-N
InChi Code
InChI=1S/C10H17N3O5/c11-6(9(15)16)3-4-8(14)12-13-5-1-2-7(13)10(17)18/h6-7H,1-5,11H2,(H,12,14)(H,15,16)(H,17,18)/t6-,7+/m0/s1
SMILES Code
O=C(O)[C@@H]1N(NC(CC[C@H](N)C(O)=O)=O)CCC1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 259.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Mayengbam S, Yang H, Barthet V, Aliani M, House JD. Identification, characterization, and quantification of an anti-pyridoxine factor from flaxseed using ultrahigh-performance liquid chromatography-mass spectrometry. J Agric Food Chem. 2014 Jan 15;62(2):419-26. doi: 10.1021/jf404786v. Epub 2014 Jan 2. PubMed PMID: 24354394. 2: Parsons JL, Klosterman HJ, Ninnemann JL. Bacterial inhibition by linatine and other hydrazino acids. Antimicrob Agents Chemother (Bethesda). 1967;7:415-21. PubMed PMID: 5596166. 3: Klosterman HJ, Lamoureux GL, Parsons JL. Isolation, characterization, and synthesis of linatine. A vitamin B6 antagonist from flaxseed (Linum usitatissimum). Biochemistry. 1967 Jan;6(1):170-7. PubMed PMID: 6071768. 4: Mayengbam S, Raposo S, Aliani M, House JD. Oral exposure to the anti-pyridoxine compound 1-amino D-proline further perturbs homocysteine metabolism through the transsulfuration pathway in moderately vitamin B₆ deficient rats. J Nutr Biochem. 2015 Mar;26(3):241-9. doi: 10.1016/j.jnutbio.2014.10.014. Epub 2014 Dec 3. PubMed PMID: 25524630.