Synonym
Licoflavone C; 8-Prenylapigenin;
IUPAC/Chemical Name
5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-en-1-yl)-4H-chromen-4-one
InChi Key
MEHHCBRCXIDGKZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H18O5/c1-11(2)3-8-14-15(22)9-16(23)19-17(24)10-18(25-20(14)19)12-4-6-13(21)7-5-12/h3-7,9-10,21-23H,8H2,1-2H3
SMILES Code
O=C1C=C(C2=CC=C(O)C=C2)OC3=C(C/C=C(C)\C)C(O)=CC(O)=C13
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Preparing Stock Solutions
The following data is based on the
product
molecular weight
338.35
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Scarpato R, Paganucci L, Bertoli A, Fiore L, Pistelli L, Federico G. Licoflavone C attenuates the genotoxicity of cancer drugs in human peripheral lymphocytes. Phytother Res. 2008 Dec;22(12):1650-4. doi: 10.1002/ptr.2546. PubMed PMID: 18979523.
2: Edziri H, Mastouri M, Mahjoub MA, Mighri Z, Mahjoub A, Verschaeve L. Antibacterial, antifungal and cytotoxic activities of two flavonoids from Retama raetam flowers. Molecules. 2012 Jun 13;17(6):7284-93. doi: 10.3390/molecules17067284. PubMed PMID: 22695233.
3: Yin YZ, Wang RS, Chen RD, Qiao LR, Yang L, Wang CM, Dai JG. [Chemical constituents from cell suspension cultures of Cudrania tricuspidata]. Zhongguo Zhong Yao Za Zhi. 2012 Dec;37(24):3734-7. Chinese. PubMed PMID: 23627169.
4: Li M, Wu X, Wang X, Shen T, Ren D. Two novel compounds from the root bark of Morus alba L. Nat Prod Res. 2018 Jan;32(1):36-42. doi: 10.1080/14786419.2017.1327862. Epub 2017 May 19. PubMed PMID: 28521570.
