CLX 0921 | CAS#249886-47-3 | PPAR gamma agonist

MedKoo Cat#: 529416 | Name: CLX 0921

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CLX 0921 is a peroxisome proliferator-activated receptor（PPAR）gamma agonist potentially for the treatment of type 2 diabetes.

Chemical Structure

CLX 0921

CAS#249886-47-3

Theoretical Analysis

MedKoo Cat#: 529416

Name: CLX 0921

CAS#: 249886-47-3

Chemical Formula: C28H25NO7S

Exact Mass: 519.1352

Molecular Weight: 519.56

Elemental Analysis: C, 64.73; H, 4.85; N, 2.70; O, 21.56; S, 6.17

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

CLX-0921; THR-0921; CLX0921; THR0921; CLX 0921; THR 0921

IUPAC/Chemical Name

methyl (E)-3-(3,5-dimethoxyphenyl)-2-(4-(4-((2,4-dioxothiazolidin-5-yl)methyl)phenoxy)phenyl)acrylate

InChi Key

IVAQJHSXBVHUQT-ZVHZXABRSA-N

InChi Code

InChI=1S/C28H25NO7S/c1-33-22-12-18(13-23(16-22)34-2)14-24(27(31)35-3)19-6-10-21(11-7-19)36-20-8-4-17(5-9-20)15-25-26(30)29-28(32)37-25/h4-14,16,25H,15H2,1-3H3,(H,29,30,32)/b24-14+

SMILES Code

O=C(OC)/C(C1=CC=C(OC2=CC=C(CC(SC(N3)=O)C3=O)C=C2)C=C1)=C/C4=CC(OC)=CC(OC)=C4

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 519.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Gratzke C, Streng T, Stief CG, Downs TR, Alroy I, Rosenbaum JS, Andersson KE, Hedlund P. Effects of cannabinor, a novel selective cannabinoid 2 receptor agonist, on bladder function in normal rats. Eur Urol. 2010 Jun;57(6):1093-100. doi: 10.1016/j.eururo.2010.02.027. PubMed PMID: 20207474. 2: Gratzke C, Streng T, Stief CG, Alroy I, Limberg BJ, Downs TR, Rosenbaum JS, Hedlund P, Andersson KE. Cannabinor, a selective cannabinoid-2 receptor agonist, improves bladder emptying in rats with partial urethral obstruction. J Urol. 2011 Feb;185(2):731-6. doi: 10.1016/j.juro.2010.09.080. PubMed PMID: 21168864.