MedKoo Cat#: 461456 | Name: Perimetazine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Perimetazine has central nervous system depressent effects such as sedative and muscle relaxant effects.

Chemical Structure

Perimetazine
CAS#13093-88-4 (free base)

Theoretical Analysis

MedKoo Cat#: 461456

Name: Perimetazine

CAS#: 13093-88-4 (free base)

Chemical Formula: C22H28N2O2S

Exact Mass: 384.1871

Molecular Weight: 384.53

Elemental Analysis: C, 68.72; H, 7.34; N, 7.29; O, 8.32; S, 8.34

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
58-33-3 (HCl); 13093-88-4 (free base)
Synonym
Perimetazine; AN 1317; AN-1317; AN1317; RP 9159; RP-9159; RP9159;
IUPAC/Chemical Name
1-(3-(2-methoxy-10H-phenothiazin-10-yl)-2-methylpropyl)piperidin-4-ol
InChi Key
WYRWAVVTDKZRIJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H28N2O2S/c1-16(14-23-11-9-17(25)10-12-23)15-24-19-5-3-4-6-21(19)27-22-8-7-18(26-2)13-20(22)24/h3-8,13,16-17,25H,9-12,14-15H2,1-2H3
SMILES Code
OC1CCN(CC(C)CN2C3=C(C=CC=C3)SC4=CC=C(OC)C=C24)CC1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 384.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Ikeda S, Murayama S. [Neuropharmacological studies of perimetazine]. Nihon Yakurigaku Zasshi. 1976;72(1):113-26. Japanese. PubMed PMID: 986345. 2: Naito J, Kuga T. [Pharmacological analysis of effects of perimetazine on isolated smooth muscle]. Nihon Yakurigaku Zasshi. 1976 Nov;72(8):1013-23. Japanese. PubMed PMID: 14870. 3: Volle L, Baudinot J, Lardet C, Frairot A. [Study of a new neuroleptic in a department of general medicine of adults: perimetazine (1317 A.N.)]. Lyon Med. 1970 May 24;223(21):1083-6. French. PubMed PMID: 5421811. 4: Rainaut J. [Study of 1317-A.N., Leptryl. Possibilities in psychiatric treatment with a new phenothiazine: perimetazine or 1317 A.N]. Mars Med. 1970;107(4):353-61. French. PubMed PMID: 4912083. 5: Kappas A. On the mechanisms of induced aneuploidy in Aspergillus nidulans and validation of tests for genomic mutations. Prog Clin Biol Res. 1989;318:377-84. PubMed PMID: 2696976. 6: Picard JM, Pagnon F, Helmer J, Henry A. [Perimetazin in cardiac surgery with extracorporeal circulation]. Anesth Analg (Paris). 1972 May-Jun;29(3):395-9. French. PubMed PMID: 4405448. 7: Bourgeois M, Sicart AM. [Trial of perimethazine, A. N. 1317 or R. P. 9159 (Leptril) in psychiatry]. Bord Med. 1970 Feb;3(2):515-22. French. PubMed PMID: 5425878.