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MedKoo Cat#: 461408 | Name: Ronipamil

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ronipamil is an analogue of verapamil that acts as a calcium entry blocker.

Chemical Structure

Ronipamil
Ronipamil
CAS#85247-77-4

Theoretical Analysis

MedKoo Cat#: 461408

Name: Ronipamil

CAS#: 85247-77-4

Chemical Formula: C32H48N2

Exact Mass: 60.3817

Molecular Weight: 460.75

Elemental Analysis: C, 83.42; H, 10.50; N, 6.08

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Ronipamil; Ronipamilo;
IUPAC/Chemical Name
2-(3-(methyl(phenethyl)amino)propyl)-2-phenyltetradecanenitrile
InChi Key
KLBJRPVUPJXXCM-UHFFFAOYSA-N
InChi Code
InChI=1S/C32H48N2/c1-3-4-5-6-7-8-9-10-11-18-25-32(29-33,31-22-16-13-17-23-31)26-19-27-34(2)28-24-30-20-14-12-15-21-30/h12-17,20-23H,3-11,18-19,24-28H2,1-2H3
SMILES Code
CCCCCCCCCCCCC(C1=CC=CC=C1)(CCCN(C)CCC2=CC=CC=C2)C#N
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 460.75 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Lefer AM, Papanicolaou G. Beneficial actions of two novel calcium entry blockers in the isolated perfused hypoxic cat liver. Methods Find Exp Clin Pharmacol. 1985 Feb;7(2):59-63. PubMed PMID: 3838786. 2: Curtis MJ, Walker MJ, Yuswack T. Actions of the verapamil analogues, anipamil and ronipamil, against ischaemia-induced arrhythmias in conscious rats. Br J Pharmacol. 1986 Jun;88(2):355-61. PubMed PMID: 3755364; PubMed Central PMCID: PMC1916825. 3: Hock CE, Daitch JS, Lefer AM. Salutary effects of two verapamil analogs in traumatic shock. Pharm Res. 1985 May;2(3):130-4. doi: 10.1023/A:1016363316777. PubMed PMID: 24272690. 4: Dumont L, Williams JS, Vaghy PL, Schwartz A. Characteristics of the phenylalkylamine binding site in canine cardiac sarcolemmal membranes. Basic Res Cardiol. 1988 Jul-Aug;83(4):369-75. PubMed PMID: 2847707. 5: Corsini A, Granata A, Fumagalli R, Paoletti R. Calcium antagonists and low density lipoproteins metabolism by human fibroblasts and by human hepatoma cell line HEP G2. Pharmacol Res Commun. 1986 Jan;18(1):1-16. PubMed PMID: 3006091.