TG41 | CAS#850339-33-2 | GABAA receptor modulator

MedKoo Cat#: 563501 | Name: TG41

Description:

WARNING: This product is for research use only, not for human or veterinary use.

TG41 is a positive modulator of GABAA receptors.

Chemical Structure

TG41

CAS#850339-33-2

Theoretical Analysis

MedKoo Cat#: 563501

Name: TG41

CAS#: 850339-33-2

Chemical Formula: C18H13BrCl2N2O2

Exact Mass: 437.9537

Molecular Weight: 440.11

Elemental Analysis: C, 49.12; H, 2.98; Br, 18.16; Cl, 16.11; N, 6.37; O, 7.27

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

TG41; TG-41; TG 41;

IUPAC/Chemical Name

ethyl 2-(4-bromophenyl)-1-(2,4-dichlorophenyl)-1H-imidazole-4-carboxylate

InChi Key

ZXNGHKGWIDGULE-UHFFFAOYSA-N

InChi Code

InChI=1S/C18H13BrCl2N2O2/c1-2-25-18(24)15-10-23(16-8-7-13(20)9-14(16)21)17(22-15)11-3-5-12(19)6-4-11/h3-10H,2H2,1H3

SMILES Code

O=C(C1=CN(C2=CC=C(Cl)C=C2Cl)C(C3=CC=C(Br)C=C3)=N1)OCC

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 440.11 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Abdullah JM, Zhang J. The GABA A receptor subunits heterologously expressed in Xenopus oocytes. Mini Rev Med Chem. 2013 Apr 1;13(5):744-8. Review. PubMed PMID: 23373649. 2: Mascia MP, Asproni B, Busonero F, Talani G, Maciocco E, Pau A, Cerri R, Sanna E, Biggio G. Ethyl 2-(4-bromophenyl)-1-(2,4-dichlorophenyl)-1H-4-imidazolecarboxylate is a novel positive modulator of GABAA receptors. Eur J Pharmacol. 2005 Jun 15;516(3):204-11. PubMed PMID: 15967425.