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MedKoo Cat#: 598687 | Name: Leupeptin acid

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Leupeptin acid is a metabolite of Leupeptin.

Chemical Structure

Leupeptin acid
CAS#24125-28-8

Theoretical Analysis

MedKoo Cat#: 598687

Name: Leupeptin acid

CAS#: 24125-28-8

Chemical Formula: C20H38N6O5

Exact Mass: 442.2904

Molecular Weight: 442.56

Elemental Analysis: C, 54.28; H, 8.66; N, 18.99; O, 18.08

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
39740-82-4 (HCl) 55123-66-5 (free base) 1082207-96-2 (hemisulfate hydrate) 103476-89-7 (hemisulfate) 24365-47-7 (free base)
Synonym
Leupeptin acid; Acetyl-L-leu-L-leu-L-arg;
IUPAC/Chemical Name
acetyl-L-leucyl-L-leucyl-L-arginine
InChi Key
OLNJKAXRBXUBTB-JYJNAYRXSA-N
InChi Code
InChI=1S/C20H38N6O5/c1-11(2)9-15(24-13(5)27)17(28)26-16(10-12(3)4)18(29)25-14(19(30)31)7-6-8-23-20(21)22/h11-12,14-16H,6-10H2,1-5H3,(H,24,27)(H,25,29)(H,26,28)(H,30,31)(H4,21,22,23)/t14-,15-,16-/m0/s1
SMILES Code
N=C(N)NCCC[C@@H](C(O)=O)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC(C)=O)=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 442.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Suzukake K, Hori M, Tamemasa O, Umezawa H. Purification and properties of an enzyme reducing leupeptin acid to leupeptin. Biochim Biophys Acta. 1981 Oct 13;661(2):175-81. PubMed PMID: 7295735. 2: Suzukake K, Fujiyama T, Hayashi H, Hori M, Umezawa H. Biosynthesis of leupeptin. II Purification and properties of leupeptin acid synthetase. J Antibiot (Tokyo). 1979 May;32(5):523-30. PubMed PMID: 43319. 3: Suzukake K, Takada M, Hori M, Umezawa H. Biosynthesis of leupeptin. IV. Is protein turnover in leupeptin producer cells affected by leupeptin? J Antibiot (Tokyo). 1980 Oct;33(10):1172-6. PubMed PMID: 7451369.

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