Spiroalmotriptan is a medication primarily used to treat acute migraine attacks. It belongs to the class of triptans, which are selective serotonin receptor agonists, and works by binding to serotonin receptors in the brain, particularly the 5-HT1B and 5-HT1D receptors. By activating these receptors, spiroalmotriptan helps constrict dilated blood vessels in the brain, reducing inflammation and pain associated with migraines. Its mechanism of action also involves inhibiting the release of certain neuropeptides, which contribute to the migraine process.
MedKoo Cat#: 146018
Name: Spiroalmotriptan
CAS#: 1309457-18-8
Chemical Formula: C17H25N3O3S
Exact Mass: 351.1600
Molecular Weight: 351.47
Elemental Analysis: C, 58.10; H, 7.17; N, 11.96; O, 13.66; S, 9.12
The following data is based on the product molecular weight 351.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
