MedKoo Cat#: 563464 | Name: AC-93253 iodide
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

AC-93253 iodide is a SIRT2 selective inhibitor. It acts by significantly enhancing acetylation of tubulin, p53, and histone H4.

Chemical Structure

AC-93253 iodide
AC-93253 iodide
CAS#108527-83-9 (iodide)

Theoretical Analysis

MedKoo Cat#: 563464

Name: AC-93253 iodide

CAS#: 108527-83-9 (iodide)

Chemical Formula: C23H25IN2S

Exact Mass: 488.0783

Molecular Weight: 488.43

Elemental Analysis: C, 56.56; H, 5.16; I, 25.98; N, 5.74; S, 6.56

Price and Availability

Size Price Availability Quantity
10mg USD 450.00 2 Weeks
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Related CAS #
61173-17-9 (cation) 108527-83-9 (iodide)
Synonym
AC-93253 iodide; AC 93253 iodide; AC93253 iodide;
IUPAC/Chemical Name
3-ethyl-2-((E)-3-((E)-1,3,3-trimethylindolin-2-ylidene)prop-1-en-1-yl)benzo[d]thiazol-3-ium iodide
InChi Key
TWBRXRGFFUATNI-UHFFFAOYSA-M
InChi Code
InChI=1S/C23H25N2S.HI/c1-5-25-19-13-8-9-14-20(19)26-22(25)16-10-15-21-23(2,3)17-11-6-7-12-18(17)24(21)4;/h6-16H,5H2,1-4H3;1H/q+1;/p-1
SMILES Code
CC[N+]1=C(/C=C/C=C2N(C)C3=C(C=CC=C3)C/2(C)C)SC4=CC=CC=C14.[I-]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 488.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Lai YH, Lin SY, Wu YS, Chen HW, Chen JJW. AC-93253 iodide, a novel Src inhibitor, suppresses NSCLC progression by modulating multiple Src-related signaling pathways. J Hematol Oncol. 2017 Nov 13;10(1):172. doi: 10.1186/s13045-017-0539-3. PubMed PMID: 29132432; PubMed Central PMCID: PMC5683468.