Lettucenin A | CAS#97915-46-3 | sesquiterpenoid lactone phytoalexin

MedKoo Cat#: 598622 | Name: Lettucenin A

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lettucenin A is a sesquiterpenoid lactone phytoalexin.

Chemical Structure

Lettucenin A

CAS#97915-46-3

Theoretical Analysis

MedKoo Cat#: 598622

Name: Lettucenin A

CAS#: 97915-46-3

Chemical Formula: C15H12O3

Exact Mass: 240.0786

Molecular Weight: 240.25

Elemental Analysis: C, 74.99; H, 5.03; O, 19.98

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Lettucenin A;

IUPAC/Chemical Name

6-methyl-9-methylene-2-oxo-2,7,8,9-tetrahydroazuleno[4,5-b]furan-3-carbaldehyde

InChi Key

PATCUDSVUMFCMB-UHFFFAOYSA-N

InChi Code

InChI=1S/C15H12O3/c1-8-3-6-11-12(7-16)15(17)18-14(11)13-9(2)4-5-10(8)13/h3,6-7H,2,4-5H2,1H3

SMILES Code

O=CC1=C2C(OC1=O)=C3C(CCC3=C(C)C=C2)=C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 240.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Mai F, Glomb MA. Lettucenin sesquiterpenes contribute significantly to the browning of lettuce. J Agric Food Chem. 2014 May 21;62(20):4747-53. doi: 10.1021/jf500413h. Epub 2014 May 12. PubMed PMID: 24818869. 2: Bestwick CS, Bennett MH, Mansfield JW. Hrp Mutant of Pseudomonas syringae pv phaseolicola Induces Cell Wall Alterations but Not Membrane Damage Leading to the Hypersensitive Reaction in Lettuce. Plant Physiol. 1995 Jun;108(2):503-516. PubMed PMID: 12228488; PubMed Central PMCID: PMC157369. 3: Sessa RA, Bennett MH, Lewis MJ, Mansfield JW, Beale MH. Metabolite profiling of sesquiterpene lactones from Lactuca species. Major latex components are novel oxalate and sulfate conjugates of lactucin and its derivatives. J Biol Chem. 2000 Sep 1;275(35):26877-84. PubMed PMID: 10858433. 4: Bennett MH, Mansfield JW, Lewis MJ, Beale MH. Cloning and expression of sesquiterpene synthase genes from lettuce (Lactuca sativa L.). Phytochemistry. 2002 Jun;60(3):255-61. PubMed PMID: 12031443. 5: Mai F, Glomb MA. Structural and Sensory Characterization of Novel Sesquiterpene Lactones from Iceberg Lettuce. J Agric Food Chem. 2016 Jan 13;64(1):295-301. doi: 10.1021/acs.jafc.5b05128. Epub 2016 Jan 4. PubMed PMID: 26727458.