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MedKoo Cat#: 598564 | Name: Penicillin G benzathine anhydrous
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Penicillin G benzathine anhydrous is a semisynthetic antibiotic prepared by combining the sodium salt of penicillin G with N,N'-dibenzylethylenediamine.

Chemical Structure

Penicillin G benzathine anhydrous
Penicillin G benzathine anhydrous
CAS#1538-09-6 (benzathine anhydrous)

Theoretical Analysis

MedKoo Cat#: 598564

Name: Penicillin G benzathine anhydrous

CAS#: 1538-09-6 (benzathine anhydrous)

Chemical Formula: C48H56N6O8S2

Exact Mass: 0.0000

Molecular Weight: 909.13

Elemental Analysis: C, 63.42; H, 6.21; N, 9.24; O, 14.08; S, 7.05

Price and Availability

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50mg USD 450.00 2 weeks
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Related CAS #
1538-09-6 (benzathine anhydrous) 113-98-4 (potassium) 6130-64-9 (procaine hydrate) Penicillin G-d5 K (d5 potassium) 3344-16-9 (hydrabamine)
Synonym
Penicillin G benzathine anhydrous; Bicillin I; Extenicilline; NCI-C56100; NCI C56100; NCIC56100l Benzethacil;
IUPAC/Chemical Name
N1,N2-dibenzylethane-1,2-diamine bis((2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate)
InChi Key
BVGLIYRKPOITBQ-ANPZCEIESA-N
InChi Code
InChI=1S/2C16H18N2O4S.C16H20N2/c2*1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;1-3-7-15(8-4-1)13-17-11-12-18-14-16-9-5-2-6-10-16/h2*3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);1-10,17-18H,11-14H2/t2*11-,12+,14-;/m11./s1
SMILES Code
O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC(CC3=CC=CC=C3)=O)N1C2=O)O.O=C([C@@H](C(C)(C)S[C@]4([H])[C@@H]5NC(CC6=CC=CC=C6)=O)N4C5=O)O.C7(CNCCNCC8=CC=CC=C8)=CC=CC=C7
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 909.13 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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Empirical Therapy Versus Tailored Therapy of Helicobacter pylori in Korea: Results of the K-CREATE Study. Helicobacter. 2024 Jul-Aug;29(4):e13126. doi: 10.1111/hel.13126. PMID: 39143948. 5: Tian LL, Xing BB, Zhang YM, Zhao JP. [Distribution and antibiotic resistance analysis of Gram positive cocci in bloodstream infections in a hospital in Inner Mongolia]. Zhonghua Yu Fang Yi Xue Za Zhi. 2024 Aug 6;58(8):1242-1246. Chinese. doi: 10.3760/cma.j.cn112150-20231120-00354. PMID: 39142895. 6: Deimel LP, Moynié L, Sun G, Lewis V, Turner A, Buchanan CJ, Burnap SA, Kutuzov M, Kobras CM, Demyaneko Y, Mohammed S, Stracy M, Struwe WB, Baldwin AJ, Naismith J, Davis BG, Sattentau QJ. Covalent penicillin-protein conjugates elicit anti-drug antibodies that are clonally and functionally restricted. Nat Commun. 2024 Aug 10;15(1):6851. doi: 10.1038/s41467-024-51138-7. PMID: 39127707; PMCID: PMC11316840. 7: Li C, Ma Y, Fan C, He C, Ma S. 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PMID: 39107511; PMCID: PMC11303562. 11: Singu BS, Pieper CH, Verbeeck RK, Ette EI. Predictors of gentamicin therapy failure in neonates with sepsis. Pharmacol Res Perspect. 2024 Aug;12(4):e1250. doi: 10.1002/prp2.1250. PMID: 39105353; PMCID: PMC11301262. 12: Barzilai A, Toubiana S, Dalal A, Baum S. The role of piperacillin/tazobactam in the treatment of Hidradenitis suppurativa. J Dermatolog Treat. 2024 Dec;35(1):2363318. doi: 10.1080/09546634.2024.2363318. Epub 2024 Aug 5. PMID: 39103159. 13: Daschner C, Schübler AS, Jung M, Ayasse N, Yücel G, Husain-Syed F, Leipe J, Krämer BK, Yazdani B. Severe Leptospirosis with Acute Kidney Injury - A Case Description and Literature Review. Nephron. 2024 Aug 5. doi: 10.1159/000540300. Epub ahead of print. PMID: 39102808. 14: Rasmussen HC, Hanberg P, Lilleøre JG, Petersen EK, Hvistendahl MA, Jørgensen AR, Stilling M, Bue M. 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