MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 461324 | Name: Ridazolol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ridazolol is a cardioselective and vasodilating beta adrenergic blocker.

Chemical Structure

Ridazolol
Ridazolol
CAS#83395-21-5

Theoretical Analysis

MedKoo Cat#: 461324

Name: Ridazolol

CAS#: 83395-21-5

Chemical Formula: C15H18Cl2N4O3

Exact Mass: 372.0756

Molecular Weight: 373.23

Elemental Analysis: C, 48.27; H, 4.86; Cl, 19.00; N, 15.01; O, 12.86

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Ridazolol; Ridazololum;
IUPAC/Chemical Name
4-chloro-5-((2-((3-(2-chlorophenoxy)-2-hydroxypropyl)amino)ethyl)amino)pyridazin-3(2H)-one
InChi Key
UUWABVCZFXKHSU-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H18Cl2N4O3/c16-11-3-1-2-4-13(11)24-9-10(22)7-18-5-6-19-12-8-20-21-15(23)14(12)17/h1-4,8,10,18,22H,5-7,9H2,(H2,19,21,23)
SMILES Code
O=C1C(Cl)=C(NCCNCC(O)COC2=CC=CC=C2Cl)C=NN1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 373.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Unger P, Berkenboom G, Fontaine J. Study of ridazolol on isolated canine and human coronary arteries. Cardiovasc Drugs Ther. 1989 Jun;3(3):459-64. PubMed PMID: 2577285. 2: Fach WA, Starke E, Becker HJ. [Duration of the effect and dose-response relationship of ridazolol in patients with coronary heart disease]. Z Kardiol. 1992 Jun;81(6):320-5. German. PubMed PMID: 1353933. 3: Haerer W, Henze E, Stauch M. [The effect of a combination of ridazolol and molsidomine on hemodynamics and left ventricular function in dilated cardiomyopathy]. Arzneimittelforschung. 1989 Jun;39(6):714-6. German. PubMed PMID: 2570582. 4: Rommel T, Demisch L. Influence of chronic beta-adrenoreceptor blocker treatment on melatonin secretion and sleep quality in patients with essential hypertension. J Neural Transm Gen Sect. 1994;95(1):39-48. PubMed PMID: 7857585. 5: Haerer W, Henze E, Stauch M. [Hemodynamics and ventricular function in dilated cardiomyopathies following administration of the new beta-blocker ridazolol]. Herz. 1988 Feb;13(1):54-8. German. PubMed PMID: 2897323. 6: Schulz W, Löffler K, Voleske P, Resag K. [Determination of duration of action of beta blockers with Holter-ECG registration]. Arzneimittelforschung. 1991 May;41(5):489-93. German. PubMed PMID: 1680325.