IUPAC/Chemical Name
(2R,3s,4S)-pentane-1,2,3,4,5-pentayl pentakis(4-hydroxybenzoate)
InChi Key
VWTLXEPPPUFDHF-SGIQEJNWSA-N
InChi Code
VWTLXEPPPUFDHF-SGIQEJNWSA-N
SMILES Code
O=C(OC[C@H](OC(C1=CC=C(O)C=C1)=O)[C@H](OC(C2=CC=C(O)C=C2)=O)[C@H](OC(C3=CC=C(O)C=C3)=O)COC(C4=CC=C(O)C=C4)=O)C5=CC=C(O)C=C5
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Preparing Stock Solutions
The following data is based on the
product
molecular weight
752.68
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Silvestri I, Albonici L, Ciotti M, Lombardi MP, Sinibaldi P, Manzari V, Orlando P, Carretta F, Strazzullo G, Grippo P. Antimitotic and antiviral activities of Kelletinin A in HTLV-1 infected MT2 cells. Experientia. 1995 Nov 15;51(11):1076-80. PubMed PMID: 7498449.
2: Orlando P, Carretta F, Grippo P, Cimino G, De Stefano S, Strazzullo G. Kelletinin I and kelletinin A from the marine mollusc Buccinulum corneum are inhibitors of eukaryotic DNA polymerase alpha. Experientia. 1991 Jan 15;47(1):64-6. PubMed PMID: 1999246.
3: De Petrocellis L, Orlando P, Pierobon P, De Falco M, Ruggiero AM, Stefano GS, Tino A, Grippo P. Kelletinin A, from the marine mollusc Buccinulum corneum, promotes differentiation in Hydra vulgaris. Res Commun Mol Pathol Pharmacol. 1999 Jan;103(1):17-28. PubMed PMID: 10440567.
4: Orlando P, Strazzullo G, Carretta F, De Falco M, Grippo P. Inhibition mechanisms of HIV-1, Mo-MuLV and AMV reverse transcriptases by Kelletinin A from Buccinulum corneum. Experientia. 1996 Aug 15;52(8):812-7. PubMed PMID: 8774754.
