Synonym
Azacyclonol hydrochloride; Azacyclonol HCl
IUPAC/Chemical Name
4-Piperidinemethanol, alpha,alpha-diphenyl-, hydrochloride
InChi Key
LBRAWKGGVUCSOX-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H21NO.ClH/c20-18(15-7-3-1-4-8-15,16-9-5-2-6-10-16)17-11-13-19-14-12-17;/h1-10,17,19-20H,11-14H2;1H
SMILES Code
OC(C1=CC=CC=C1)(C2=CC=CC=C2)C3CCNCC3.[H]Cl
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Preparing Stock Solutions
The following data is based on the
product
molecular weight
303.83
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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13: ALLIN TG Jr, POGGE RC. The use of azacyclonol and pipradrol in general practice. Int Rec Med Gen Pract Clin. 1956 Apr;169(4):222-30. PubMed PMID: 13318734.
14: Kuhlman JJ Jr, Levine B, Klette KL, Magluilo J Jr, Kalasinsky KS, Smith ML. Measurement of azacyclonol in urine and serum of humans following terfenadine (Seldane) administration using gas chromatography-mass spectrometry. J Chromatogr. 1992 Jul 24;578(2):207-13. PubMed PMID: 1400799.
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17: DRESEL PE. The effect of azacyclonol on some cardiovascular and metabolic actions of epinephrine. J Pharmacol Exp Ther. 1959 Mar;125(3):208-12. PubMed PMID: 13642259.
18: [Azacyclonol (chlorhydrate). Chlorhydrate of diphenyl (4-piperidyl) methanol]. Ann Pharm Fr. 1968 Jul-Aug;26(7):583-4. French. PubMed PMID: 5729721.
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